Talk:BGDA Lecture - Development of the Nervous System: Difference between revisions
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==Early Brain Structure== | |||
===Primary Vesicles=== | |||
[[Image:CNS primary vesicles.jpg|600px]] | |||
* rostral neural tube forms 3 primary brain vesicles (week 4) | |||
* 3 primary vesicles: '''prosencephalon''' (forebrain), '''mesencephalon''' (midbrain), '''rhombencephalon''' (hindbrain) | |||
See also the [[#Week 4 - Stage 13|week 4 embryo movie]]. | |||
===Secondary Vesicles=== | |||
[[File:CNS secondary vesicles.jpg|600px]] | |||
From the 3 primary vesicles developing to form 5 secondary vesicles (week 5) | |||
* prosencephalon- '''telencephalon''' (endbrain, forms cerebral hemispheres), '''diencephalon''' (betweenbrain, forms optic outgrowth) | |||
* '''mesencephalon''' | |||
* rhombencephalon- '''metencephalon''' (behindbrain), '''myelencephalon''' (medullabrain) | |||
See also the [[#Week 4 - Stage 16|week 6 embryo movie]]. | |||
===Textbook collapse table=== | ===Textbook collapse table=== |
Revision as of 15:55, 18 May 2017
2017
Monday 29 May 2017 09:00 AM - 10:00 AM Development of the nervous system Kensington - Rex Vowels Theatre Hill, Mark
Neuropores
Cranial Neuropore | Caudal Neuropore |
---|---|
(stage 11) | (stage 12) |
- cranial (anterior) neuropore closes before caudal (posterior)
- failure to close - Neural Tube Defects (NTD), severity dependent upon level, spina bifida anancephaly (More? [neuron2.htm Neural Abnormalities])
- found that supplementation of maternal diet with folate reduces incidence of NTDs
- A randomised controlled trial conducted by the Medical Research Council of the United Kingdom demonstrated a 72% reduction in risk of recurrence by periconceptional (ie before and after conception) folic acid supplementation (4mg daily).
- Women who have one infant with a neural tube defect have a significantly increased risk of recurrence (40-50 per thousand compared with 2 per thousand for all births)
Early Brain Structure
Primary Vesicles
- rostral neural tube forms 3 primary brain vesicles (week 4)
- 3 primary vesicles: prosencephalon (forebrain), mesencephalon (midbrain), rhombencephalon (hindbrain)
See also the week 4 embryo movie.
Secondary Vesicles
From the 3 primary vesicles developing to form 5 secondary vesicles (week 5)
- prosencephalon- telencephalon (endbrain, forms cerebral hemispheres), diencephalon (betweenbrain, forms optic outgrowth)
- mesencephalon
- rhombencephalon- metencephalon (behindbrain), myelencephalon (medullabrain)
See also the week 6 embryo movie.