Talk:BGDA Lecture - Development of the Nervous System

2017

eMed URL Link: http://emed.med.unsw.edu.au/Map.nsf/wFrameset?OpenFrameSet&Frame=NotesView&Src=/Map.nsf/0/159748002E587E4ECA257339000628C9?OpenDocument&Login

Monday 29 May 2017 09:00 AM - 10:00 AM Development of the nervous system Kensington - Rex Vowels Theatre Hill, Mark

Neural groove closing to neural tube, early week 4
(Stage 10)

Relative brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)

Neuropores

Cranial Neuropore	Caudal Neuropore
(stage 11)	(stage 12)

• cranial (anterior) neuropore closes before caudal (posterior)
• failure to close - Neural Tube Defects (NTD), severity dependent upon level, spina bifida anancephaly (More? [neuron2.htm Neural Abnormalities])
• found that supplementation of maternal diet with folate reduces incidence of NTDs
  • A randomised controlled trial conducted by the Medical Research Council of the United Kingdom demonstrated a 72% reduction in risk of recurrence by periconceptional (ie before and after conception) folic acid supplementation (4mg daily).
  • Women who have one infant with a neural tube defect have a significantly increased risk of recurrence (40-50 per thousand compared with 2 per thousand for all births)

Early Brain Structure

Primary Vesicles

• rostral neural tube forms 3 primary brain vesicles (week 4)
• 3 primary vesicles: prosencephalon (forebrain), mesencephalon (midbrain), rhombencephalon (hindbrain)

See also the week 4 embryo movie.

Secondary Vesicles

From the 3 primary vesicles developing to form 5 secondary vesicles (week 5)

• prosencephalon- telencephalon (endbrain, forms cerebral hemispheres), diencephalon (betweenbrain, forms optic outgrowth)
• mesencephalon
• rhombencephalon- metencephalon (behindbrain), myelencephalon (medullabrain)

See also the week 6 embryo movie.

Textbook collapse table

Textbooks

UNSW Embryology Hill, M.A. (2020). UNSW Embryology (20th ed.) Retrieved March 9, 2021, from https://embryology.med.unsw.edu.au Neural Links: ectoderm | neural | neural crest | ventricular | sensory | Stage 22 | gliogenesis | neural fetal | Medicine Lecture - Neural | Lecture - Ectoderm | Lecture - Neural Crest | Lab - Early Neural | neural abnormalities | folic acid | iodine deficiency | Fetal Alcohol Syndrome | neural postnatal | neural examination | Histology | Historic Neural | Category:Neural The Developing Human: Clinically Oriented Embryology Moore, K.L., Persaud, T.V.N. & Torchia, M.G. (2015). The developing human: clinically oriented embryology (10th ed.). Philadelphia: Saunders. (links only function with UNSW connection) The Developing Human: Clinically Oriented Embryology (10th edn)  UNSW Students have online access to the current 10th edn. through the UNSW Library subscription (with student Zpass log-in). APA Citation: Moore, K.L., Persaud, T.V.N. & Torchia, M.G. (2015). The developing human: clinically oriented embryology (10th ed.). Philadelphia: Saunders. Links: PermaLink | UNSW Embryology Textbooks | Embryology Textbooks | UNSW Library Introduction to the Developing Human First Week of Human Development Second Week of Human Development Third Week of Human Development Fourth to Eighth Weeks of Human Development Fetal Period Placenta and Fetal Membranes Body Cavities and Diaphragm Pharyngeal Apparatus, Face, and Neck Respiratory System Alimentary System Urogenital System Cardiovascular System Skeletal System Muscular System Development of Limbs Nervous System Development of Eyes and Ears Integumentary System Human Birth Defects Common Signaling Pathways Used During Development Appendix : Discussion of Clinically Oriented Problems Chapter 17 Nervous System Larsen's Human Embryology Schoenwolf, G.C., Bleyl, S.B., Brauer, P.R., Francis-West, P.H. & Philippa H. (2015). Larsen's human embryology (5th ed.). New York; Edinburgh: Churchill Livingstone.(links only function with UNSW connection) Larsen's Human Embryology (5th edn)  UNSW students have full access to this textbook edition through UNSW Library subscription (with student Zpass log-in). APA Citation: Schoenwolf, G.C., Bleyl, S.B., Brauer, P.R., Francis-West, P.H. & Philippa H. (2015). Larsen's human embryology (5th ed.). New York; Edinburgh: Churchill Livingstone. Links: PermaLink | UNSW Embryology Textbooks | Embryology Textbooks | UNSW Library Gametogenesis, Fertilization, and First Week Second Week: Becoming Bilaminar and Fully Implanting Third Week: Becoming Trilaminar and Establishing Body Axes Fourth Week: Forming the Embryo Principles and Mechanisms of Morphogenesis and Dysmorphogenesis Fetal Development and the Fetus as Patient Development of the Skin and Its Derivatives Development of the Musculoskeletal System Development of the Central Nervous System Development of the Peripheral Nervous System Development of the Respiratory System and Body Cavities Development of the Heart Development of the Vasculature Development of the Gastrointestinal Tract Development of the Urinary System Development of the Reproductive System Development of the Pharyngeal Apparatus and Face Development of the Ears Development of the Eyes Development of the Limbs Chapter 9 Development of the Central Nervous System Chapter 10 Development of the Peripheral Nervous System More Textbooks?