Sensory - Taste Development: Difference between revisions
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* '''Fate mapping of mammalian embryonic taste bud progenitors'''<ref><pubmed>19363153</pubmed></ref>"Mammalian taste buds have properties of both epithelial and neuronal cells, and are thus developmentally intriguing. Taste buds differentiate at birth within epithelial appendages, termed taste papillae, which arise at mid-gestation as epithelial thickenings or placodes. ...we demonstrate that Shh-expressing embryonic taste placodes are taste bud progenitors, which give rise to at least two different adult taste cell types, but do not contribute to taste papillae. Strikingly, placodally descendant taste cells disappear early in adult life." | * '''Fate mapping of mammalian embryonic taste bud progenitors'''<ref><pubmed>19363153</pubmed></ref>"Mammalian taste buds have properties of both epithelial and neuronal cells, and are thus developmentally intriguing. Taste buds differentiate at birth within epithelial appendages, termed taste papillae, which arise at mid-gestation as epithelial thickenings or placodes. ...we demonstrate that Shh-expressing embryonic taste placodes are taste bud progenitors, which give rise to at least two different adult taste cell types, but do not contribute to taste papillae. Strikingly, placodally descendant taste cells disappear early in adult life." | ||
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==Development Timing== | |||
These are human embryonic timings<ref><pubmed>8955790</pubmed></ref>, not clinical which is based on last menstral period +2 weeks. | |||
'''Week 6''' - gustatory papilla, caudal midline near the foramen caecum | |||
'''Week 6-7''' - nerve fibers approach the lingual epithelium | |||
'''Week 8''' - nerves penetrate epitheilai basal lamina and synapse with undifferentiated, elongated, epithelial cells (taste bud progenitor cell) | |||
'''Week 10''' - shallow grooves above the taste bud primordium | |||
'''Week 12''' - first differentiated epithelial cells (Type II and III) | |||
'''Week 12 -13''' - maximum synapses between cells and afferent nerve fibers | |||
'''Week 14 - 15''' - taste pores develop, mucous | |||
'''Week 18''' - substance P detected in dermal papillae, not in taste bud primordia | |||
'''3rd Trimester''' - | |||
==Gustatory cranial sensory neurons== | ==Gustatory cranial sensory neurons== |
Revision as of 09:07, 26 March 2011
Introduction
These notes introduce the development of the sense of taste which can divided into five basic tastes: bitter, salty, sweet, umami (savoury) and sour. Current research appears to have displaced the historic concept of a tongue "map".
A study in rat suggests that neonatal changes in circumvallate papillae may result in postnatal changes in "taste".[3] In frogs, a large taste disc (TD) is the largest vertebrate gustatory organ. Postnatally, the sense of taste is also closely related to the sense of smell.
Taste Links: Introduction | Student project | Tongue Development | Category:Taste | ||
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Senses Links: Introduction | placode | Hearing and Balance hearing | balance | vision | smell | taste | touch | Stage 22 | Category:Sensory |
Some Recent Findings
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Development Timing
These are human embryonic timings[5], not clinical which is based on last menstral period +2 weeks.
Week 6 - gustatory papilla, caudal midline near the foramen caecum
Week 6-7 - nerve fibers approach the lingual epithelium
Week 8 - nerves penetrate epitheilai basal lamina and synapse with undifferentiated, elongated, epithelial cells (taste bud progenitor cell)
Week 10 - shallow grooves above the taste bud primordium
Week 12 - first differentiated epithelial cells (Type II and III)
Week 12 -13 - maximum synapses between cells and afferent nerve fibers
Week 14 - 15 - taste pores develop, mucous
Week 18 - substance P detected in dermal papillae, not in taste bud primordia
3rd Trimester -
Gustatory cranial sensory neurons
Cranial nerves VII, IX and X have dual embryonic origins and provide both gustatory (taste) and non-gustatory (touch, pain, temperature) sensory innervation to the oral cavity of vertebrates.
Gustatory Neurons
- originate from epibranchial placodes
- innervate taste buds
- project centrally to the rostral nucleus of the solitary tract (NTS)
General Epithelial Innervation of the oral cavity
- originate from cranial neural crest
- innervation to the oropharynx
- project to non-gustatory hindbrain regions (spinal trigeminal nucleus)
(text based on: Embryonic origin of gustatory cranial sensory neurons.[6])
Stage 22
Section (B4) through head showing tongue and head structures.
References
Reviews
Articles
Search PubMed
Search May 2010
- Taste System Development - All (320) Review (64) Free Full Text (78)
- Tongue Development - All (2804) Review (258) Free Full Text (519)
Search Pubmed: Taste System Development | Tongue Development
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Cite this page: Hill, M.A. (2024, May 9) Embryology Sensory - Taste Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Sensory_-_Taste_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G