Neural Crest - Enteric Nervous System
Introduction
The neural crest are bilaterally paired strips of cells arising in the ectoderm at the margins of the neural tube. These cells migrate to many different locations and differentiate into many cell types within the embryo. This means that many different systems (neural, skin, teeth, head, face, heart, adrenal glands, gastrointestinal tract) will also have a contribution fron the neural crest cells.
In the body region, neural crest cells also contribute the peripheral nervous system (both neurons and glia) of the enteric nervous system.
Neural Crest Links: neural crest | Lecture - Early Neural | Lecture - Neural Crest Development | Lecture Movie | Schwann cell | adrenal | melanocyte | peripheral nervous system | enteric nervous system | cornea | cranial nerve neural crest | head | skull | cardiac neural crest | Nicole Le Douarin | Neural Crest Movies | neural crest abnormalities | Category:Neural Crest | |||
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Some Recent Findings
Neural Crest Migration
Movie Source: Original Neural Crest movies kindly provided by Paul Kulesa.[2]
Related Movies: Migration 01 | Migration 02 | Migration 03 | Migration 04 | Migration 05 | Migration 06 | Migration 07
Development Overview
The following cranial and trunk data is based upon 185 serially sectioned staged (Carnegie) human embryos.[3]
Cranial Neural Crest
- stage 9 - an indication of mesencephalic neural crest
- stage 10 - trigeminal, facial, and postotic components
- stage 11 - crest-free zones are soon observable in rhombomere 1, 3, and 5
- stage 12 - rhombomeres 6 and 7 neural crest migrate to pharyngeal arch 3 and then rostrad to the truncus arteriosus
- stage 13 - nasal crest and the terminalis-vomeronasal complex are last of the cranial crest to appear
stages 9-14 - otic vesicle primordium descends
Trunk Neural Crest
Spinal ganglia increase in number over time and are in phase with the somites, though not their centre. There are 3 migratory pathways: ventrolateral between dermatomyotome and sclerotome, ventromedial between neural tube and sclerotomes, and lateral between surface ectoderm and dermatomyotome.
- stage 13 - about 19 present
- stage 14 - about 33 present
- stage 15-23 - 30–35 ganglia
References
- ↑ <pubmed></pubmed>
- ↑ <pubmed>10683170</pubmed>
- ↑ <pubmed>17848161</pubmed>| PMC2375817 | J Anat.
Reviews
<pubmed>20683859</pubmed> <pubmed>19387688</pubmed> <pubmed>16225807</pubmed> <pubmed>12593987</pubmed> <pubmed>11336393</pubmed>
Articles
Search PubMed
Search Pubmed: Enteric Neural Development
Additional Images
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Cite this page: Hill, M.A. (2024, April 28) Embryology Neural Crest - Enteric Nervous System. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_Crest_-_Enteric_Nervous_System
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G