ANAT2341 Lab 6: Difference between revisions

Revision as of 11:37, 19 July 2018

1. QUIZ

2. Guest Lecturer - Dr Kirsty Walters

Dr Kitsty Walters

Dr Kirsty Walters is a Senior Lecturer in Women’s and Children’s Health at the University of New South Wales (UNSW), Sydney, specialising in the field of female reproduction and ovarian function.

Background:

Dr Walters was awarded her PhD in 2005 from Edinburgh University, Scotland, and was then recruited by the ANZAC Research Institute (ARI) to undertake a post-doctoral position investigating the role androgens play in regulating female reproduction and physiology. In February 2016 the UNSW recruited her to head up the Ovarian Biology Laboratory based in the Wallace Wurth, which forms part of the world-leading biomedical precinct at UNSW.

Research interests:

Dr Walters’ research involves using customized genetic mouse models in combination with clinical samples and trials to dissect out the fundamental mechanisms regulating female reproduction and polycystic ovary syndrome (PCOS). In particular, her research has focused on understanding the role androgens play in regulating female fertility and PCOS. Findings from this research will identify therapeutic targets for improved treatment of female infertility and the wide range of health issues associated with PCOS, including obesity, insulin resistance, type 2 diabetes and cardiovascular risk.

References

Walters KA; Edwards MC; Tesic D; Caldwell ASL; Jimenez M; Smith JT; Handelsman DJ, 2018, 'The Role of Central Androgen Receptor Actions in Regulating the Hypothalamic-Pituitary-Ovarian Axis', Neuroendocrinology, vol. 106, pp. 389 - 400, http://dx.doi.org/10.1159/000487762 (link is external)

Walters KA; Bertoldo MJ; Handelsman DJ, 2018, 'Evidence from animal models on the pathogenesis of PCOS', Best Practice and Research: Clinical Endocrinology and Metabolism, vol. 32, pp. 271 - 281, http://dx.doi.org/10.1016/j.beem.2018.03.008 (link is external)

Bertoldo MJ; Walters KA; Ledger WL; Gilchrist RB; Mermillod P; Locatelli Y, 2018, 'In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies', Reproductive BioMedicine Online, vol. 36, pp. 491 - 499, http://dx.doi.org/10.1016/j.rbmo.2018.01.014 (link is external)

Upton DH; Walters KA; McTavish KJ; Holt J; Handelsman DJ; Allan CM, 2018, 'Reproductive failure in mice expressing transgenic follicle-stimulating hormone is not caused by loss of oocyte quality.', Biol Reprod, vol. 98, pp. 491 - 500, http://dx.doi.org/10.1093/biolre/ioy015 (link is external)

Walters KA; Handelsman DJ, 2018, 'Role of androgens in the ovary', Molecular and Cellular Endocrinology, vol. 465, pp. 36 - 47, http://dx.doi.org/10.1016/j.mce.2017.06.026 (link is external)

@@ Line 3: / Line 3: @@
-== 2. Guest Lecturer - Dr Tennille Luker-Sibbritt==
+== 2. Guest Lecturer - Dr Kirsty Walters==
 {|
-| width=185px| [[File:Tennille_Sibbritt.jpg|180px]]
+| width=185px| [[File:Kirsty.jpeg|180px]]
-Dr Tennille Luker - Sibbritt
+Dr Kitsty Walters
-[[Media:TennilleSibbritt ANAT2341 forprint.pdf|Lecture Slides]]
+| Dr Kirsty Walters is a Senior Lecturer in Women’s and Children’s Health at the University of New South Wales (UNSW), Sydney, specialising in the field of female reproduction and ovarian function.
-| Dr Tennille Sibbritt is researcher at the Children's Medical Research Institute (CMRI) at Westmead. She graduated with a PhD in RNA Biology in 2015. In 2016, she started working in the Embryology Unit at the CMRI, where she is building a gene regulatory network for head development using mouse embryos.
-A gene regulatory network is a collection of molecular species that interact with each other and other species to regulate gene expression. They play a central role in the morphogenesis, regionalisation, and patterning of the brain and craniofacial structures, which rely on the function of various transcription factors; these transcription factors constitute the central nodes of these gene regulatory networks.
-Tennille’s research involves the use of high-throughput sequencing technologies and CRISPR-Cas9 genomic editing in combination with fast-tracked mouse chimera analysis.
+Background:
-|}
-===References===
+Dr Walters was awarded her PhD in 2005 from Edinburgh University, Scotland, and was then recruited by the ANZAC Research Institute (ARI) to undertake a post-doctoral position investigating the role androgens play in regulating female reproduction and physiology. In February 2016 the UNSW recruited her to head up the Ovarian Biology Laboratory based in the Wallace Wurth, which forms part of the world-leading biomedical precinct at UNSW.
-Recent book chapters and articles relating to craniofacial development from the Embryology Unit.
-<pubmed>26969997</pubmed>
-<pubmed>25977363</pubmed>
-<pubmed>21228006</pubmed>
-==3. Group Projects==
+Research interests:
-Following the Mid-semester break (23 Sep - 2 Oct) '''each student''' will prepare their own peer assessment of the other group projects. This means that your own project page should be in a format ready for assessment after the break.
+Dr Walters’ research involves using customized genetic mouse models in combination with clinical samples and trials to dissect out the fundamental mechanisms regulating female reproduction and polycystic ovary syndrome (PCOS). In particular, her research has focused on understanding the role androgens play in regulating female fertility and PCOS. Findings from this research will identify therapeutic targets for improved treatment of female infertility and the wide range of health issues associated with PCOS, including obesity, insulin resistance, type 2 diabetes and cardiovascular risk.
+|}
-Note that you will have time then to make changes to your project based upon this feedback before the final assessment.
+===References===
+Walters KA; Edwards MC; Tesic D; Caldwell ASL; Jimenez M; Smith JT; Handelsman DJ, 2018, 'The Role of Central Androgen Receptor Actions in Regulating the Hypothalamic-Pituitary-Ovarian Axis', Neuroendocrinology, vol. 106, pp. 389 - 400, http://dx.doi.org/10.1159/000487762 (link is external)
-===Peer Assessment===
-You will prepare these assessments using either the assessors criteria or your own designated criteria. It should represent a balanced assessment of the project identifying the strengths and weaknesses of each project.
-Your individual assessment should be added in 2 places.
+Walters KA; Bertoldo MJ; Handelsman DJ, 2018, 'Evidence from animal models on the pathogenesis of PCOS', Best Practice and Research: Clinical Endocrinology and Metabolism, vol. 32, pp. 271 - 281, http://dx.doi.org/10.1016/j.beem.2018.03.008 (link is external)
-# Firstly, anonymously to the Discussion page of each project (no signatures).
+Bertoldo MJ; Walters KA; Ledger WL; Gilchrist RB; Mermillod P; Locatelli Y, 2018, 'In-vitro regulation of primordial follicle activation: challenges for fertility preservation strategies', Reproductive BioMedicine Online, vol. 36, pp. 491 - 499, http://dx.doi.org/10.1016/j.rbmo.2018.01.014 (link is external)
-# Secondly, on your own student page where the course coordinator will allocate you a mark as part of your individual assessment component for the course.
+Upton DH; Walters KA; McTavish KJ; Holt J; Handelsman DJ; Allan CM, 2018, 'Reproductive failure in mice expressing transgenic follicle-stimulating hormone is not caused by loss of oocyte quality.', Biol Reprod, vol. 98, pp. 491 - 500, http://dx.doi.org/10.1093/biolre/ioy015 (link is external)
+Walters KA; Handelsman DJ, 2018, 'Role of androgens in the ovary', Molecular and Cellular Endocrinology, vol. 465, pp. 36 - 47, http://dx.doi.org/10.1016/j.mce.2017.06.026 (link is external)
-{{Group Assessment Criteria table}}
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 {{2017ANAT2341 footer}}