ANAT2341 Lab 6: Difference between revisions

From Embryology
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===References===
===References===
Recent book chapters and articles relating to craniofacial development from the Embryology Unit include:
Recent book chapters and articles relating to craniofacial development from the Embryology Unit.
 
P. P. Tam, N. Fossat, E. Wilkie, D. A. Loebel, C. K. Ip, M. Ramialison, Formation of the Embryonic Head in the Mouse: Attributes of a Gene Regulatory Network, Curr. Top. Dev. Biol., 117 (2016) 497-521.
 
N. Fossat, C.K. Ip, V. J. Jones, J.B. Studdert, P. L. Khoo, S. L. Lewis, M. Power, K. Tourle, D. A. Loebel, K. M. Kwan, R. R. Behringer, P. P. Tam N., Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo, Development, 142 (2015) 2069-2079.
 
N. Fossat, V. Jones, P. L. Khoo, D. Bogani, A. Hardy, K. Steiner, M. Mukhopadhyay, H. Westphal, P. M. Nolan, R. Arkell, P. P. Tam, Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo, Development, 138 (2011) 667-676.


<pubmed>26969997</pubmed>
<pubmed>25977363</pubmed>
<pubmed>21228006</pubmed>




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{{2017ANAT2341 footer}}

Revision as of 11:37, 18 July 2017

1. QUIZ

2. Guest Lecturer - Dr Tenille Luker - Sibbritt

Tennille Sibbritt.jpg

Dr Tenille Luker - Sibbritt

Dr Tennille Sibbritt is researcher at the Children's Medical Research Institute (CMRI) at Westmead. She graduated with a PhD in RNA Biology in 2015. In 2016, she started working in the Embryology Unit at the CMRI, where she is building a gene regulatory network for head development using mouse embryos.

A gene regulatory network is a collection of molecular species that interact with each other and other species to regulate gene expression. They play a central role in the morphogenesis, regionalisation, and patterning of the brain and craniofacial structures, which rely on the function of various transcription factors; these transcription factors constitute the central nodes of these gene regulatory networks.

Tennille’s research involves the use of high-throughput sequencing technologies and CRISPR-Cas9 genomic editing in combination with fast-tracked mouse chimera analysis.

References

Recent book chapters and articles relating to craniofacial development from the Embryology Unit.

<pubmed>26969997</pubmed> <pubmed>25977363</pubmed> <pubmed>21228006</pubmed>



 2017 ANAT2341 - Timetable | Course Outline | Group Projects | Moodle | Tutorial 1 | Tutorial 2 | Tutorial 3

Labs: 1 Fertility and IVF | 2 ES Cells to Genome Editing | 3 Preimplantation and Early Implantation | 4 Reproductive Technology Revolution | 5 Cardiac and Vascular Development | 6 CRISPR-Cas9 | 7 Somitogenesis and Vertebral Malformation | 8 Organogenesis | 9 Genetic Disorders | 10 Melanocytes | 11 Stem Cells | 12 Group

Lectures: 1 Introduction | 2 Fertilization | 3 Week 1/2 | 4 Week 3 | 5 Ectoderm | 6 Placenta | 7 Mesoderm | 8 Endoderm | 9 Research Technology | 10 Cardiovascular | 11 Respiratory | 12 Neural crest | 13 Head | 14 Musculoskeletal | 15 Limb | 16 Renal | 17 Genital | 18 Endocrine | 19 Sensory | 20 Fetal | 21 Integumentary | 22 Birth | 23 Stem cells | 24 Revision

 Student Projects: 1 Cortex | 2 Kidney | 3 Heart | 4 Eye | 5 Lung | 6 Cerebellum