Gastrointestinal Tract - Abnormalities
Introduction
The "simple tube" of the gastrointestinal tract and its associated organs have many different tract and organ specific abnormalities. Note that as this system begins function (digestively) postnatally, unless there is a determined genetic history within the family, several abnormalities only become evident postnatally. Due to the complex nature (different germ layer contributions, organogenisis) of the growth, elongation and folding of the tract, there are also several mechanical disorders of folding (rotation).
Australian Statistics
File:Pie git.gifThe mouth (cleft lip, cleft palate) is part of the digestive tract, but more accurately reflects an abnormality of face formation. (More? [face2.htm Face Abnormalities]). | The pie diagram shows the relative contribution of major gastrointestinal tract abnormalities as a percentage of the total number of congenital abnormalities in Australia beween 1981 - 92.
Note that the digestive system represents approximately 6% of all major congenital abnormalities. One of the most common abnormalities occurring in (2% - 3% population) is [#Meckel Meckel's Diverticulum]. |
Gastroschisis
(paraomphalocele, laparoschisis, abdominoschisis, abdominal hernia) A developmental abnormality, which occurs as an abdominal wall defect associated with evisceration of the intestine (2.5 cases/10,000 births). Usually occurs as an isolated defect, defects in other organ systems have been reported in up to 35% of children. There are several theories as to the cause of this abdominal wall defect, including recently failure of the yolk sac and related vitelline structures to be incorporated into the umbilical stalk.[1]
Omphalocele
An abnormality appearing similar to gastroschisis, involves a lack of normal return of the bowel to the abdominal cavity and has a different position relative to the umbilical cord.
References
- ↑ <pubmed>19419415</pubmed>
Reviews
Articles
<pubmed>19419414</pubmed> <pubmed>17230493</pubmed>
Search PubMed
Search Pubmed: gastrointestinal tract abnormalities
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Cite this page: Hill, M.A. (2024, June 26) Embryology Gastrointestinal Tract - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Gastrointestinal_Tract_-_Abnormalities
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G