Carnegie Stage 8 - "Dobbin" Embryo
|Embryology - 17 Nov 2019 Expand to Translate|
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The historic "Dobbin" embryo was named after Dr Roy Dobbin (Cairo, Egypt) who originally provided the specimen to Dr James Hill.
The notes, photographs and sections are within the Hill Collection that form a part of the embryological collection relocated in 2004 to the Museum fur Naturkunde, Berlin and incorporated with the Hubrecht Collection.
- Links: Hill Embryo H91 | Carnegie stage 8 | Hill Collection | Dr James Hill | Hubrecht Collection | Museum fur Naturkunde - Embryological Collection
The clinical history supplied by Dr. Dobbin is as follows: “ Coitus, 6.10.23 ; effort probably causing abortion, 21.10.23; first bleeding, 22.10.23; abortion (painless), 23.10.23." Although an abortion, we see no reason to regard the specimen as other than perfectly normal.
The chorionic vesicle (which was preserved in spirit) was, when received, somewhat ﬂattened and shrunken. Except over a small area on one side (approximately 3 x 2 mm in diameter), which was almost bare, the vesicle possessed a fairly uniform covering of short, close~set, branched villi, to which at one point a small fragment of blood-clot adhered. Including the villi, its dimensions in alcohol were as follows : 11.5 mm (in long diameter) x 8.5 mm (in short diameter) x 45 mm (in thickness). After clearing in oil of cedar-wood, the corresponding internal diameters were 9 mm x 5.5 mm x 2.5 mm.
The vesicle, after being photographed and drawn, was dehydrated and cleared in oil of cedar-wood. A small portion of the chorion, including the bare area, was then carefully removed, and through the opening so made it was possible, fortunately enough, to locate the embryo under the binocular dissecting microscope. The embryo was then isolated along with the segment of the chorion to which it was attached, and stereo-photographs were successfully taken of it, in the cleared condition in oil of cedar-wood.
Hill catalogue number - (original) H159 | (new) H91
The original embryology catalogue numbers were consolidated and renumbered by Peter Hill's daughter, another embryologist.
Embryo - Chorionic Vesicle
These are stereo photographs of the whole and opened vesicle before sectioning.
|Further descriptions of the "Dobbin" Embryo characterised as (Carnegie Stage 8) can be found in the following papers:
Hill JP. and Florian J. The development of head-process and prochordal plate in man (1931) J Anat. 65(2): 242-6. PMID 17104317
Hill JP. and Florian J. A young human embryo (embryo dobbin) with head-process and prochordal plate. (1931) Phil. Tran. Roy. Soc. London B, 219: 443-486.
|Note the rostral end of notochordal process was at first mistaken for prechordal plate, see published correction.
See page - Carnegie Stage 8 - "Dobbin" Embryo
Transverse section, scale bar is 500 micron.
- Histology Slide: 2-47 | 2-48 | 2-49 | 2-50 | 2-51 | 2-52 | 2-53 | 2-54 | 2-55 | 2-56 | 2-57 | 2-70 | 2-75 | 2-80 | 2-89
- Hill JP. and Florian J. The development of head-process and prochordal plate in man (1931) J Anat. 65(2): 242-6. PMID 17104317
- Hill JP. and Florian J. A young human embryo (embryo dobbin) with head-process and prochordal plate. (1931) Phil. Tran. Roy. Soc. London B, 219: 443-486.
- Hill JP. and Florian J. Further note on the pro-chordal plate in man. (1931) J. Anat., 46: 46-47. PMID 17104356
Cite this page: Hill, M.A. (2019, November 17) Embryology Carnegie Stage 8 - "Dobbin" Embryo. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_Stage_8_-_%22Dobbin%22_Embryo
- © Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G