Somatic Cell Nuclear Transfer

Introduction

Page Under Development

Early Human Zygote, with 2 pronuclei

The first diploid cell that forms following fertilization by fusion of the haploid oocyte (egg) and spermatozoa (sperm) resulting in the combination of their separate genomes. The first image shows the cell with the 2 pronuclei still present before fusion enclosed within the zona pellucida. In humans, this cell then undergoes a series of mitotic cell divisions, still enclosed within the zona pellucida, during the first few days of development to form 2 blastomeres then a solid cell mass called the morula.

Some Recent Findings

Number of blastomeres and distribution of microvilli in cloned mouse embryos during compaction^[1] "We concluded that: (i) the cleavage of blastomeres in cloned embryos was slow at least before compaction; (ii) the distribution of microvilli in cloned, normal, parthenogenetic, and tetraploid embryos was coherent before and after compaction; and (iii) the initiation of compaction in somatic cell nuclear transfer (SCNT) embryos was delayed compared with that of intracytoplasmic sperm injection (ICSI) embryos."

Epigenetics

References

↑ <pubmed>20735894</pubmed>

Journals

Zygote An international journal dedicated to the rapid publication of original research in early embryology, Zygote covers interdisciplinary studies in animals and humans, from gametogenesis through fertilization to gastrulation.

Reviews

Articles

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June 2010 "zygote" All (6213) Review (651) Free Full Text (1543)

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Glossary Links

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Cite this page: Hill, M.A. (2024, May 5) Embryology Somatic Cell Nuclear Transfer. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Somatic_Cell_Nuclear_Transfer

What Links Here?

[1] <pubmed>20735894</pubmed>

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