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Gastrointestinal Tract Epithelium Development
This simple animation shows the early development of the gastrointestinal tract tube wall. Abnormalities of this process can lead to atresia, stenosis or duplication within the gastrointestinal tract.
- the endodermal epithelial wall proliferates.
- the early tract lumen is transiently lost (week 6)
- vaculated spaces form (week 7 to 8).
- gut tube completely recanalised (week 9).
- epithelium differentiates.
Links: MP4 version | gastrointestinal abnormalities | Gastrointestinal Tract Development | Movies
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Abnormalities
| Online Editor - There are several recent animal models that suggest that this historic model, first put forward by Julius Tandler (1900), does not adequately explain all congenital abnormalities of the lumen of the gastrointestinal tract.
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Julius Tandler (1869 – 1936)
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Atresia
An interruption of the lumen (esophageal atresia, duodenal atresia, extrahepatic biliary atresia, anorectal atresia). Pyloric atresia (PA) - a very rare condition (incidence 1 in 100,000 newborns) and about 1% of all intestinal atresias.
Stenosis
A narrowing of the lumen (duodenal stenosis, pyloric stenosis).
Duplication
An incomplete recanalization resulting in parallel lumens, this is really a specialized form of stenosis.
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Cite this page: Hill, M.A. (2023, December 4) Embryology Gastrointestinal Tract Growth Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Gastrointestinal_Tract_Growth_Movie
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- © Dr Mark Hill 2023, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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