2010 BGD Practical 12 - Abnormalities: Difference between revisions

Revision as of 08:36, 1 June 2010

Introduction

Prenatal diagnosis are the clinical tools used to determine both normal and abnormal development. There are a growing number of both prenatal and neonatal clinical screening methods for many disorders of development.

Statistics - Top Ten

Australian Data 1981-92

The ten most frequently reported birth defects in Victoria between 2003-2004 (More? Australian Statistics - Victoria)

Hypospadias
Obstructive Defects of the Renal Pelvis or Obstructive Genitourinary Defects
Ventricular Septal Defect
Congenital Dislocated Hip
Trisomy 21 or Down syndrome
Hydrocephalus
Cleft Palate
Trisomy 18 or Edward Syndrome - multiple abnormalities of the heart, diaphragm, lungs, kidneys, ureters and palate 86% discontinued.
Renal Agenesis/Dysgenesis - reduction in neonatal death and stillbirth since 1993 may be due to the more severe cases being identified in utero and being represented amongst the increased proportion of terminations (approximately 31%).
Cleft Lip and Palate - occur with another defect in 33.7% of cases.

Additional Information

Links: UNSW Embryology - Abnormal Development | Tutorial - Applied Embryology and Teratology

The links below are to more detailed information about some of the current prenatal diagnostic techniques and their applications.

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link

2010 BGD: Lecture 1 | Lecture 2 | Practical 3 | Practical 6 | Practical 12

Cite this page: Hill, M.A. (2024, April 26) Embryology 2010 BGD Practical 12 - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/2010_BGD_Practical_12_-_Abnormalities

What Links Here?

@@ Line 31: / Line 31: @@
 '''Links:''' [http://embryology.med.unsw.edu.au/Defect/page1.htm UNSW Embryology - Abnormal Development] | [http://embryology.med.unsw.edu.au/Medicine/BGD2tutorial.htm Tutorial - Applied Embryology and Teratology]
-===Stillbirths===
-'''Commentary: reducing the world's stillbirths.''' Goldenberg RL, McClure EM, Belizán JM. BMC Pregnancy Childbirth. 2009 May 7;9 Suppl 1:S1. [http://www.ncbi.nlm.nih.gov/pubmed/19426464 PMID: 19426464] | [ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679407/ PMC2679407]
-:"One of the major success stories of modern obstetrics in high-income countries in the last 5 decades is the reduction of stillbirths from rates as high as 50 per 1000 births to about 5 per 1000 births today. Fetal mortality associated with obstructed labour, asphyxia, hypertension, diabetes, Rh disease, placental abruption, post-term pregnancies and infections such as syphilis all have declined. Much of this success has occurred in term births in the intrapartum period so that most stillbirths in high-income countries now occur in the antepartum period and are pre-term."