Neural Crest - Melanocyte Development: Difference between revisions
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==Introduction== | ==Introduction== | ||
Melanocytes provide the pigment melanin to keratinocytes in the skin epithelium. These cells are neural crest in origin and recent research suggests that they are derived from the same population that Schwann cells are derived. | Melanocytes provide the pigment melanin to keratinocytes in the skin epithelium. These cells are neural crest in origin and recent research suggests that they are derived from the same population that Schwann cells are derived. |
Revision as of 07:39, 4 February 2012
Introduction
Melanocytes provide the pigment melanin to keratinocytes in the skin epithelium. These cells are neural crest in origin and recent research suggests that they are derived from the same population that Schwann cells are derived.
Schwann cells wrap around nerve axon processes outside of the central nervous system. These cells in development originate from neural crest cells migrating out along the developing nerve fibers and these cells differentiate to form myelin sheaths that surround the mature nerve.
The cells are named after their original discoverer a German physiologist Theodor Schwann (1810 - 1882).
Neural Crest Links: neural crest | Lecture - Early Neural | Lecture - Neural Crest Development | Lecture Movie | Schwann cell | adrenal | melanocyte | peripheral nervous system | enteric nervous system | cornea | cranial nerve neural crest | head | skull | cardiac neural crest | Nicole Le Douarin | Neural Crest Movies | neural crest abnormalities | Category:Neural Crest | |||
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Some Recent Findings
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Mouse Skin Melanocytes
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Mouse melanocyte migration[3] | Movie Mouse Skin - Melanoblast Migration E14.5[4] |
=Zebrafish Melanocytes
Erbb3b gene is required to establish melanocyte stem cells in the embryo that are responsible for regenerating melanocytes after melanocytes are ablated in the larval zebrafish. Because this adult stem cell is not required for the development of embryonic melanocytes, we conclude that adult melanocyte stem cells develop in parallel to the embryonic tissues that they regulate.[5]
References
- ↑ <pubmed>21249204</pubmed>| PMC3020956 | PLoS One
- ↑ <pubmed>19837037</pubmed>
- ↑ <pubmed>16277556</pubmed>| PLoS Biol.
- ↑ <pubmed>20067551</pubmed>| PMC2859249
- ↑ <pubmed>19578401</pubmed>| PMC2699538 | PLoS Genet.
Reviews
<pubmed>21310010</pubmed> <pubmed>20444197</pubmed> <pubmed>20211169</pubmed> <pubmed>18935965</pubmed>
Articles
<pubmed>20848220</pubmed> <pubmed>18703590</pubmed> <pubmed>16899407</pubmed>
Search PubMed
Search Dec 2010 "Melanocyte Development" All (2294) Review (443) Free Full Text (704)
Search Pubmed: Melanocyte Development
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Cite this page: Hill, M.A. (2024, June 17) Embryology Neural Crest - Melanocyte Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_Crest_-_Melanocyte_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G