ANAT2341 Lab 2: Difference between revisions
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| Talk - The Reproductive Technology Revolution | | Talk - The Reproductive Technology Revolution | ||
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| [[File:Rob Gilchrist.jpg|left|150px]] Dr Gilchrist’s primary research interests are in the regulation of mammalian oocyte development and maturation, and the development of novel oocyte maturation techniques for infertility treatment. | | [[File:Rob Gilchrist.jpg|left|150px]] | ||
Dr Gilchrist’s primary research interests are in the regulation of mammalian oocyte development and maturation, and the development of novel oocyte maturation techniques for infertility treatment. | |||
|-bgcolor="FAF5FF" | |-bgcolor="FAF5FF" | ||
| [https://research.unsw.edu.au/people/associate-professor-robert-bruce-gilchrist UNSW Research Gateway] - [http://www.ncbi.nlm.nih.gov/pubmed/?term=Gilchrist+R%5BAuthor%5D PubMed] | | [https://research.unsw.edu.au/people/associate-professor-robert-bruce-gilchrist UNSW Research Gateway] - [http://www.ncbi.nlm.nih.gov/pubmed/?term=Gilchrist+R%5BAuthor%5D PubMed] |
Revision as of 11:02, 11 August 2016
Embryology - 15 Jun 2024 Expand to Translate |
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Week 1 to 3 Development
ANAT2341 Lab 2: Introduction | Fertilization | Week 1 | Week 2 | Online Assessment | Group Project |
Oocyte Biology Research Unit
Associate Professor Robert Gilchrist |
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Talk - The Reproductive Technology Revolution |
Dr Gilchrist’s primary research interests are in the regulation of mammalian oocyte development and maturation, and the development of novel oocyte maturation techniques for infertility treatment. |
UNSW Research Gateway - PubMed |
Recent Articles
<pubmed>26254468</pubmed>
- "The cyclic nucleotides, cAMP and cGMP, are the key molecules controlling mammalian oocyte meiosis. Their roles in oocyte biology have been at the forefront of oocyte research for decades and many of the long standing controversies in relation to the regulation of oocyte meiotic maturation are now resolved. It is now clear that the follicle prevents meiotic resumption through the actions of natriuretic peptides and cGMP inhibiting the hydrolysis of intra-oocyte cAMP and that the preovulatory gonadotrophin surge reverses these processes. The gonadotrophin surge also leads to a transient spike in cAMP in the somatic compartment of the follicle; research over the past 2 decades has conclusively demonstrated that this surge in cAMP is important for the subsequent developmental capacity of the oocyte. This is important, as oocyte in vitro maturation (IVM) systems practiced clinically do not recapitulate this cAMP surge in vitro, possibly accounting for the lower efficiency of IVM compared to clinical IVF. This review focuses in particular on this latter aspect - the role of cAMP/cGMP in the regulation of oocyte quality. We conclude that clinical practice of IVM should reflect this new understanding of the role of cyclic nucleotides, thereby creating a new generation of ART and fertility treatment options."
<pubmed>27248769</pubmed> <pubmed>27160446</pubmed>
Cumulin |
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<pubmed>26254468</pubmed>
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Objectives
Mark Hill (talk) 10:59, 11 August 2016 (AEST) The following remainder of the class on fertilisation may be worked through independently online. I will also be introducing the Group Project after the guest researcher presentation.
- Identify the key features of fertilization.
- Identify the key features of week 1 development.
- Identify the key features of week 2 development.
- Complete the individual assessment 2.
- Group assessment project.
Fertilization Reviews
- Review of sperm penetration through cumulus mass and zona pellucida
- Review of sperm-egg interaction
- Review of parthenogenesis
Human development timeline
ANAT2341 Lab 2: Introduction | Fertilization | Week 1 | Week 2 | Online Assessment | Group Project |
ANAT2341 Course Timetable | |||
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Week (Mon) | Lecture 1 (Mon 1-2pm) | Lecture 2 (Tue 3-4pm) | Practical (Fri 1-3pm) |
Week 2 (1 Aug) | Introduction | Fertilization | Lab 1 |
Week 3 (8 Aug) | Week 1 and 2 | Week 3 | Lab 2 |
Week 4 (15 Aug) | Mesoderm | Ectoderm | Lab 3 |
Week 5 (22 Aug) | Early Vascular | Placenta | Lab 4 |
Week 6 (29 Aug) | Gastrointestinal | Respiratory | Lab 5 |
Week 7 (5 Sep) | Head | Neural Crest | Lab 6 |
Week 8 (12 Sep) | Musculoskeletal | Limb Development | Lab 7 |
Week 9 (19 Sep) | Renal | Genital | Lab 8 |
Mid-semester break | |||
Week 10 (3 Oct) | Public Holiday | Stem Cells | Lab 9 |
Week 11 (10 Oct) | Integumentary | Endocrine | Lab 10 |
Week 12 (17 Oct) | Heart | Sensory | Lab 11 |
Week 13 (24 Oct) | Fetal | Birth and Revision | Lab 12 |
ANAT2341 2016: Moodle page | ECHO360 | Textbooks | Students 2016 | Projects 2016 |