Renal System - Fetal

From Embryology
Embryology - 19 Mar 2024    Facebook link Pinterest link Twitter link  Expand to Translate  
Google Translate - select your language from the list shown below (this will open a new external page)

العربية | català | 中文 | 中國傳統的 | français | Deutsche | עִברִית | हिंदी | bahasa Indonesia | italiano | 日本語 | 한국어 | မြန်မာ | Pilipino | Polskie | português | ਪੰਜਾਬੀ ਦੇ | Română | русский | Español | Swahili | Svensk | ไทย | Türkçe | اردو | ייִדיש | Tiếng Việt    These external translations are automated and may not be accurate. (More? About Translations)

Introduction

Renal Links: renal | Lecture - Renal | Lecture Movie | urinary bladder | Stage 13 | Stage 22 | Fetal | Renal Movies | Stage 22 Movie | renal histology | renal abnormalities | Molecular | Category:Renal
Historic Embryology - Renal  
1905 Uriniferous Tubule Development | 1907 Urogenital images | 1911 Cloaca | 1921 Urogenital Development | 1915 Renal Artery | 1917 Urogenital System | 1925 Horseshoe Kidney | 1926 Embryo 22 Somites | 1930 Mesonephros 10 to 12 weeks | 1931 Horseshoe Kidney | 1932 Renal Absence | 1939 Ureteric Bud Agenesis | 1943 Renal Position

Note that much of the development of the nephron occurs during the fetal period. The images below show the early fetal post-fertilization age (Week 10) (gestational age (GA Week 12) renal development. The nephron commences as a mesenchymal condensation that becomes epithelial going through a number of specific stages including later vascularization.

In humans, nephrogenesis only occurs before birth, though nephron maturation continues postnatally. Mean glomerular number shown to level at 36 weeks, increasing from about 15,000 at 15 weeks to 740,000 at 40 weeks.


Nephron development has four identifiable developmental stages:

  1. Vesicle (V) stage (13-19 weeks, second trimester)
  2. S-shaped body (S) stage ( 20-24 weeks, second trimester)
  3. Capillary loop (C) stage (25-29 weeks, third trimester)
  4. Maturation (M) stage (infants aged 1-6 months, neonatal and postnatal)

Some Recent Findings

More recent papers
Mark Hill.jpg
PubMed logo.gif

This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.

  • This search now requires a manual link as the original PubMed extension has been disabled.
  • The displayed list of references do not reflect any editorial selection of material based on content or relevance.
  • References also appear on this list based upon the date of the actual page viewing.


References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability.

More? References | Discussion Page | Journal Searches | 2019 References | 2020 References

Search term: Fetal Renal


Fetal Histology

Human fetal kidney histology 01.jpg Human fetal kidney histology 02.jpg
Human fetal kidney histology 03.jpg Human fetal kidney histology 04.jpg
Fetal Renal Links: fetal kidney histology 01 | fetal kidney histology 02 | fetal kidney histology 03 | fetal kidney histology 04


Fetal Urethra Histology

These images are a series of cross-sections through the fetal penis showing the developing urethra.

Fetal to Newborn Nephron Development

Fetal nephron development 01.jpg

After nephron development has completed and concomitant with the development of the renal papilla in the newborn, the thin ascending limb of Henle’s loops is generated as an outgrowth from the S3 segment of the proximal tubule and from the distal tubule anlage of the nephron.[1] (birds and mammals)

Kidney Endocrine
Hormone Function Comment
Renin increase angiotensin-aldosterone system paracrine, renin is released by juxtaglomerular cells
Prostaglandins decrease sodium (Na+) reabsorption paracrine, (PGE2) vasodilator regulate renal vascular reactivity
Erythropoietin increase Erythrocyte production endocrine, promotes red blood cell formation in bone marrow
1,25 (OH)2 vitamin D Calcium homeostasis endocrine, biologically active form of vitamin D
Prekallikreins increase Kinin production paracrine, act locally to induce vasodilation and contraction of smooth muscle

References

  1. Romagnani P, Lasagni L & Remuzzi G. (2013). Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nat Rev Nephrol , 9, 137-46. PMID: 23338209 DOI.

Online Textbooks

Reviews

Search PubMed

Search Pubmed: fetal kidney development | fetal renal development


Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link

Cite this page: Hill, M.A. (2024, March 19) Embryology Renal System - Fetal. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Renal_System_-_Fetal

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G