Paper - A list of normal human embryos which have been cut into serial sections
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Mall FP. A list of normal human embryos which have been cut into serial sections. (1910) Anat. Rec. 4(10): 355-367.
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A List Of Normal Human Embryos Which Have Been Cut Into Serial Sections
From the Anatomical Laboratory, Johns Hopkins University
At the Baltimore meeting of the Anatomists a number of embryologists requested The Wistar Institute to prepare a catalogue of human embryos found in various laboratories, museums and private collections in the United States, which have been sectioned and mounted for study. Accordingly a blank was prepared which was widely distributed, but replies were obtained from only those laboratories which possessed a number of series of sections. These blanks, which were not uniformly filled out, were given to me by Dr. Greenman, with the request that they be blended into a single list for the use of those interested in human embryology. Before publishing it, Dr. Huber kindly inserted a note in asking for further data, especially concerning specimens which had not yet been reported upon. The replies thus received, together with those secured by Dr. Greenman, make this list as complete as we can hope to make it at the present time.
There are about 300 specimens listed in this catalogue, and of these about one-half are well preserved. When it is considered that the series of human embryos in the embryological collection of the Anatomical Laboratory of Johns Hopkins University are selected from about 1000 abortions, it may safely be stated that but 5 per cent of them yield good serial sections of normal embryos. This list then is a selected one from about 3000 abortions, ‘ova, embryos and young foetuses.
As the embryos in a collection are usually referred to by the name of the collector, this designation has been retained in this list. By consulting therefore the list of the names of anatomists as given in this volume of it will be easy to learn where an embryo of a given length may be found.
The specimens are arranged according to their length. The medium in which they were measured is also given. The number of slides in the series is of value when requests for loans are made. The “remarks” are self explanatory. Only the chief stain is given in each case. Most of the embryos are counterstained; in Minot’s collection often with Lyons blue, in Jackson’s with congo red, in Gage’s with eosin; and in Huber’s and mine, some with eosin and some with congo red.
The specimens are arranged first, according to their crownrump length, then according to the direction of the sections, and finally according to the quality of the series. Only those marked “excellent” or “good” are of great value for study, but in special cases “fair” and “poor” series no doubt will be of value.
At a future date it may be desirable to rearrange the specimens with profile outlines of each stage, and this would be a great step in advance, for undoubtedly embryos several millimeters apart in this list may be of the same stage of development. Sooner or later we must designate embryos by their stage of development, not by their crown-rump length,—certainly not by their age, which is the Worst method of all and has brought about much confusion in embryology.
The use of a list as here given is amply justified when we consider the nature of the subject before us. Only by cooperation can we hope to advance the science of human embryology,—a subject which is of first importance to anatomists. Witness the Value of cooperation in His’s “Anatomie menschlisher Embryonen” and in Keibel and Elze’s “Normentafel zur Entwicklungsgeschichte des Menschen.” His secured embryos through the aid of various physicians and scientists, but it took a lifetime for him to make a fairly satisfactory collection of his own, as his various publications will show. Keibel and Elze borrowed embryos from different European collections and thereby were placed at an advantage. These two works are-monumental.
A selected collection of pictures of human embryos which includes several of this list is given in Kollmann’s “Handatlas der Entwicklungsgeschichte des Menschen.” At present there is in preparation a larger work on Human Embryology, in two volumes, which will be published shortly both in Leipzig and Philadelphia. About half of this treatise is being prepared by Americans and is based largely upon the collections represented in this list. This cooperative undertaking is not supported by any research grant, but those who have endowed this work with their energies know only too well that their powers would have been greatly augmented had such support been given. It may here be emphasized that efforts to promote the science of human embryology have not received financial support excepting the work of Keibel and Elze, for which they received grants from the Grand Duchy of Baden and from the Royal Prussian Academy of Sciences.
The difficulty of obtaining good material, the care and time consumed in the preparation of good series and in the study of the same (involving often the necessity of making time-consuming reconstructions) makes progress in the study of human embryology very slow. During the past 35 years His repeatedly called attention to the need of financial endowment for, and cooperation in the study of human embryology. At the first meeting of the International Association of Academies, held in Paris in 1901, His proposed that commissions be appointed for the promotion of the study of human embryology and neurology. At that meeting we saw the birth of the Brain Commission, which is working effectively for the study of the brain. A series of Interacadernic Institutes has been established, including our Wistar Institute. At that time the International Association of Academies recommended that the study of human embryology should be supported by various anatomical societies. No steps in this direction were, however, taken by the first International Anatomical Congress, which convened four years later at Geneva. Possibly the Second Congress, which meets this summer in Brussels, may be induced to consider the matter.
These statements indicate that anatomists as individuals are cooperating, but their work will progress slowly unless institutes be established to carry it on with greater vigor. is a clear one. Until the human embryo has been thoroughly investigated human anatomy will not rest upon a sound basis.
Table - Sectioned Embryos
Cite this page: Hill, M.A. (2019, June 18) Embryology Paper - A list of normal human embryos which have been cut into serial sections. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Paper_-_A_list_of_normal_human_embryos_which_have_been_cut_into_serial_sections
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