Interkinetic Nuclear Migration Movie

From Embryology
Embryology - 18 Jun 2018    Facebook link Pinterest link Twitter link  Expand to Translate  
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The intracellular movement of the nucleus in the neural progenitor cells (NPCs) of the vertebrate neuroepithelium.

The nucleus moves from the cell apex toward the base and then returns to the apex when it then divides.

The position reached by the nucleu and movement relative to the cell base may reflect the divided cell fate, either two daughter neurons or two proliferative progenitors. This is thought to be altered exposure to Notch signaling.

Links: MP4 version | Neural System Development | Notch | Mitosis | Zebrafish Development | Movies


Varun Aggarwal, Richard B Dickinson, Tanmay P Lele Concentration Sensing by the Moving Nucleus in Cell Fate Determination: A Computational Analysis. PLoS ONE: 2016, 11(2);e0149213 PubMed 26872214

Aggarwal V, Dickinson RB, Lele TP (2016) Concentration Sensing by the Moving Nucleus in Cell Fate Determination: A Computational Analysis. PLoS ONE 11(2): e0149213. doi:10.1371/journal.pone.0149213


© 2016 Aggarwal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Original model animation (S1 Movie. Motion of the Nucleus) doi:10.1371/journal.pone.0149213.s005 cropped, relabelled and converted to MP4 format (622 × 668)

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Cite this page: Hill, M.A. (2018, June 18) Embryology Interkinetic Nuclear Migration Movie. Retrieved from

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© Dr Mark Hill 2018, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G