Birth - Macrosomia
|Embryology - 17 Dec 2017 Expand to Translate|
|Google Translate - select your language from the list shown below (this will open a new external page)|
العربية | català | 中文 | 中國傳統的 | français | Deutsche | עִברִית | हिंदी | bahasa Indonesia | italiano | 日本語 | 한국어 | မြန်မာ | Pilipino | Polskie | português | ਪੰਜਾਬੀ ਦੇ | Română | русский | Español | Swahili | Svensk | ไทย | Türkçe | اردو | ייִדיש | Tiếng Việt These external translations are automated and may not be accurate. (More? About Translations)
Macrosomia (large gestational age, LGA) is a term used to describe a newborn with an excessive birth weight due to a range of known and unknown causes. There are many different definitions that have been used for to this term, generally a birth weight of 4000 to 4500 g (8 lb 13 oz to 9 lb 15 oz) or greater than 90% for gestational age after correcting for neonatal sex and ethnicity.
A recent study of USA data suggests adverse perinatal outcomes of birthweight exceeded the 97th percentile. Their definition was a "birthweight greater than 4500 g in Whites, or 4300 g in Blacks and Hispanics regardless of gestational age is the optimal threshold to define macrosomia. A birthweight greater than the 97th percentile for a given gestational age, irrespective of race is also reasonable to define macrosomia."
- Duration of gestation - growth past the due date.
- Maternal diabetes - presence of gestational diabetes; and class A, B, and C diabetes mellitus.
- Genetic Syndromes and Tumours - a range of overgrowth syndromes associated with developmental delay, tumors, and other anomalies with genetic causes and syndromes (Pallister-Killian, Beckwith-Wiedemann, Sotos, Perlman, and Simpson-Golabi-Behmel) rarely diagnosed prenatally.
Currently there is clinical research looking into the best mathematical formula, based upon ultrasound measurements, to estimate the possibility of macrosomia occurring.
- Birth Links: Introduction | Lecture - Birth | Caesarean | Preterm | Birth Weight | Birth Statistics | Australian Birth Data | Developmental Origins of Health and Disease | Macrosomia | Neonatal Diagnosis | Apgar test | Guthrie test | Neonatal Development | Stillbirth and Perinatal Death | ICD-10 Perinatal Period | Category:Birth | Maternal Diabetes
Some Recent Findings
|More recent papers|
This table shows an automated computer PubMed search using the listed sub-heading term.
References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability.
Tullio Ghi, Andrea Dall'Asta, Alice Suprani, Elisa Aiello, Andrea Musarò, Costanza Bosi, Giuseppe Pedrazzi, Ariane Kiener, Domenico Arduini, Tiziana Frusca, Giuseppe Rizzo Correlation between Subpubic Arch Angle and Mode of Delivery in Large-for-Gestational-Age Fetuses. Fetal. Diagn. Ther.: 2017; PubMed 29232667
P Blanc-Petitjean, M Salomé, C Dupont, C Crenn-Hebert, A Gaudineau, F Perrotte, P Raynal, E Clouqueur, G Beucher, B Carbonne, F Goffinet, C Le Ray Labour induction practices in France: a population-based declarative survey in 94 maternity units. J Gynecol Obstet Hum Reprod: 2017; PubMed 29196154
Tingting Wang, Hanlin Fu, Lizhang Chen, Yang Xu [Pregnancy complications among women with polycystic ovary syndrome in China: a Meta-analysis]. Zhong Nan Da Xue Xue Bao Yi Xue Ban: 2017, 42(11);1300-1310 PubMed 29187658
Laura I Parikh, Sara N Iqbal, Angie C Jelin, Rachael T Overcash, Eshetu Tefera, Melissa H Fries Third trimester ultrasound for fetal macrosomia: optimal timing and institutional specific accuracy. J. Matern. Fetal. Neonatal. Med.: 2017;1-5 PubMed 29183184
Zachary B Jenner, Amy E O'Neil Dudley, Hector Mendez-Figueroa, Viviana S Ellis, Han-Yang Chen, Suneet P Chauhan Morbidity Associated with Fetal Macrosomia among Women with Diabetes Mellitus. Am J Perinatol: 2017; PubMed 29183096
Birth Weight Classification
|Birth weight (grams)||less 500||500 – 999||1,000 – 1,499||1,500 – 1,999||2,000 – 2,499||2,500 – 2,999||3,000 – 3,499||3,500 – 3,999||4,000 – 4,499||4,500 – 4,999||5,000 or more|
Birth statistics of high birth weight infants (macrosomia) in Korea.
We used 2 data sources, namely, the hospital units (1960's to 1990's) and Statistics Korea (1993 to 2010). The analyses include the incidence of high birth weight infants (HBWIs), birth weight distribution, sex ratio, and the relationship of HBWI to maternal age. The incidence of HBWIs for the past 50 years has been dropping in Korea. The older the mother, the higher was the risk of a HBWI and LBWI. We hope that these findings would be utilized as basic data that will aid those managing HBWIs.
- Jiangfeng Ye, Lin Zhang, Yan Chen, Fang Fang, ZhongCheng Luo, Jun Zhang Searching for the definition of macrosomia through an outcome-based approach. PLoS ONE: 2014, 9(6);e100192 PubMed 24941024 | PLoS One.
- Surabhi Nanda, Ranjit Akolekar, Rita Sarquis, Ana Paula Mosconi, Kypros H Nicolaides Maternal serum adiponectin at 11 to 13 weeks of gestation in the prediction of macrosomia. Prenat. Diagn.: 2011, 31(5);479-83 PubMed 21394735
- J R Bennini, E F Marussi, R Barini, C Faro, C F A Peralta Birth-weight prediction by two- and three-dimensional ultrasound imaging. Ultrasound Obstet Gynecol: 2010, 35(4);426-33 PubMed 20069666
- Neeta Vora, Diana W Bianchi Genetic considerations in the prenatal diagnosis of overgrowth syndromes. Prenat. Diagn.: 2009, 29(10);923-9 PubMed 19609940
- Byung-Ho Kang, Joo-Young Moon, Sung-Hoon Chung, Yong-Sung Choi, Kyung-Suk Lee, Ji-Young Chang, Chong-Woo Bae Birth statistics of high birth weight infants (macrosomia) in Korea. Korean J Pediatr: 2012, 55(8);280-5 PubMed 22977440
Jennifer M Walsh, Fionnuala M McAuliffe Prediction and prevention of the macrosomic fetus. Eur. J. Obstet. Gynecol. Reprod. Biol.: 2012, 162(2);125-30 PubMed 22459652
Paul A O M De Reu, L J M Smits, H P Oosterbaan, J G Nijhuis Value of a single early third trimester fetal biometry for the prediction of birth weight deviations in a low risk population. J Perinat Med: 2008, 36(4);324-9 PubMed 18598122
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- American Academy of Family Physicians Management of Suspected Fetal Macrosomia (2001)
- MedlinePlus Topic
- A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols
Cite this page: Hill, M.A. 2017 Embryology Birth - Macrosomia. Retrieved December 17, 2017, from https://embryology.med.unsw.edu.au/embryology/index.php/Birth_-_Macrosomia
- © Dr Mark Hill 2017, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G