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Research to find correlation between vitamin D levels and successful implantation / clinical pregnancy rates in infertile women undergoing IVF treatment. Measured levels of vitamin D as determined by serum 25-hydroxy-vitamin D from total 173 women undergoing IVF at Mount Sinai Hospital, Toronto, Ontario. | Research to find correlation between vitamin D levels and successful implantation / clinical pregnancy rates in infertile women undergoing IVF treatment. Measured levels of vitamin D as determined by serum 25-hydroxy-vitamin D from total 173 women undergoing IVF at Mount Sinai Hospital, Toronto, Ontario. | ||
Serum 25-hydroxy-vitamin D samples were collected within 1 week of oocyte retrieval, and they were classified either sufficient or insufficient according to how much was present. (More than 75nmol/L was classified as being sufficient). It was found that 54.9% of the 173 women trialled on had insufficient Serum 25-hydryoxy-vitamin D levels, with only 34.7% successful implantation rate. The remaining 45.1% that had sufficient serum hydroxy-vitamin D had a 52.5% implantation rate. From these results, it was concluded that women with sufficient levels of vitamin D are significantly more likely to achieve clinical pregnancy following IVF. Vitamin D supplementation could provide an easy and cost-effective way of improving pregnancy rates; this merits further investigation. | Serum 25-hydroxy-vitamin D samples were collected within 1 week of oocyte retrieval, and they were classified either sufficient or insufficient according to how much was present. (More than 75nmol/L was classified as being sufficient). It was found that 54.9% of the 173 women trialled on had insufficient Serum 25-hydryoxy-vitamin D levels, with only 34.7% successful implantation rate. The remaining 45.1% that had sufficient serum hydroxy-vitamin D had a 52.5% implantation rate. From these results, it was concluded that women with sufficient levels of vitamin D are significantly more likely to achieve clinical pregnancy following IVF. Vitamin D supplementation could provide an easy and cost-effective way of improving pregnancy rates; this merits further investigation. | ||
===LAB 2=== | |||
[http://php.med.unsw.edu.au/embryology/index.php?title=File:Blastocyst_Hatching_in_IVF_day_6.jpeg#filelinks blastocyst hatching] |
Revision as of 22:17, 19 August 2014
Welcome to the 2014 Embryology Course!
- Links: Timetable | How to work online | One page Wiki Reference Card | Moodle
- Each week the individual assessment questions will be displayed in the practical class pages and also added here.
- Copy the assessment items to your own page and provide your answer.
- Note - Some guest assessments may require completion of a worksheet that will be handed in in class with your student name and ID.
Individual Lab Assessment |
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Lab 12 - Stem Cell Presentation Assessment | More Info | |
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Group | Comment | Mark (10) |
1/8 |
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7 |
2 |
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7.5 |
3 |
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7.5 |
4 |
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8.5 |
5 |
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8.5 |
6 |
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8.5 |
7 |
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7.5 |
LAB ATTENDANCE
--Z3463310 (talk) 12:45, 6 August 2014 (EST)
--Z3463310 (talk) 11:13, 13 August 2014 (EST)--Z3463310 (talk) 11:13, 13 August 2014 (EST)
ASSESSMENTS
Lab 1
influence of stress and anxiety on IVF
Anxiety levels and profiles on personality, level of stress hormones were measured in total of 44 women; 22 of which are undergoing IVF treatment for tubal infertility and the other 22 women (fertile) as a control. Serum prolactin and cortisol were used as stress markers, and STAI questionnaires were used to measure anxiety levels in each of the women. Comparison of profiling of personalities showed the infertile women had significantly higher scores in suspicion (p>0.05), guilt (p>0.05), and hostility (p>0.01), but lower somatic anxiety (0.05) and indirect aggression (0.05) than the fertile women as controls. The infertile women also had significantly higher levels of prolactin and cortisol throughout the menstrual cycle. In this particular study, it was concluded that infertile women when compared with fertile women showed higher stress levels and had different personality profiling results in term of suspicion, guilt, and hostility, perhaps as a result of their infertility.
correlation with IVF implantation rates and high vitamin D levels
Research to find correlation between vitamin D levels and successful implantation / clinical pregnancy rates in infertile women undergoing IVF treatment. Measured levels of vitamin D as determined by serum 25-hydroxy-vitamin D from total 173 women undergoing IVF at Mount Sinai Hospital, Toronto, Ontario. Serum 25-hydroxy-vitamin D samples were collected within 1 week of oocyte retrieval, and they were classified either sufficient or insufficient according to how much was present. (More than 75nmol/L was classified as being sufficient). It was found that 54.9% of the 173 women trialled on had insufficient Serum 25-hydryoxy-vitamin D levels, with only 34.7% successful implantation rate. The remaining 45.1% that had sufficient serum hydroxy-vitamin D had a 52.5% implantation rate. From these results, it was concluded that women with sufficient levels of vitamin D are significantly more likely to achieve clinical pregnancy following IVF. Vitamin D supplementation could provide an easy and cost-effective way of improving pregnancy rates; this merits further investigation.