User:Z3419587
Welcome to the 2014 Embryology Course!
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Lab 12 - Stem Cell Presentation Assessment | More Info | |
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8.5 |
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8.5 |
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7.5 |
Lab Attendance
Lab 1 --Z3419587 (talk) 12:45, 6 August 2014 (EST)
http://www.ncbi.nlm.nih.gov/pubmed
<pubmed>25084016</pubmed>
Lab 1 Assessment
<pubmed>25071849</pubmed> This study was done to compare the clinical outcomes between fresh embryo transfers and frozen-thawed embryo transfers.
A total of 1891 cycle contains 1150 fresh embryo transfers and 741 frozen-thawed embryo transfers were studied. All data were transferred directly to SPSS 18 and analyzed.
A long gonadotropin releasing hormone (GnRH) agonist protocol was used in all cycles. Clinical pregnancy was defined by the observation of a gestational sac with or without a fetal heartbeat on ultrasound evaluation on the 30th day after embryo transfer. The number of sacs was taken as the number of implantations.
The results showed that there was a higher clinical pregnancy rate in fresh cleavage-stage embryo transfers than frozen-thawed cleavage-stage transfers but the clinical pregnancy rates were not different significantly.
<pubmed>25077107</pubmed>
The study was done to investigate the effect of vitamin D levels on implantation and clinical pregnancy rates in infertile women following in vitro fertilization (IVF).
173 women underwent IVF were included in the study under 3 criteria, including aged 18-41 years, follicle stimulating hormone level 12 IU/L or lower and able to provide informed consent. Vitamin D was determined by serum 25(OH)D levels and samples were collected before oocyte retrieval, while implantation was determined by the presence of a gestational sac, visible by ultrasonography.
χ2 and Student t tests or Mann-Whitney U tests were used to analyze categorical and continuous variables respectively. Multi-variable logistic regression was used to evaluate the relation between serum 25(OH)D level and implantation and clinical pregnancy after adjustment fpr parameters known to influence the IVF sucesss.
The results showed that women with sufficient levels of 25(OH)D had significantly higher rates of clinical pregnancy per IVF cycle started than that with insufficient levels. It also found that implantation rates were higher, but not statistically significant, in the sufficient 25(OH)D group. Therefore, the findings suggested that women with sufficient vitamin D levels are significantly more likely to achieve clinical pregnancy following IVF.