File:Thomson1919 fig04.jpg

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Fig. 4. Human ovum in discus proligerus in anaphase of first division and commencement of metaphase of second division

x600.

Fig. 4, thickness of section 0.01 mm, stained with Weigert’s Iron Haematoxylin and Van Giesen. This represents the appearance displayed by the contiguous section to fig. 3; it calls for less detailed description since it represents many of the same details of structure already referred to in fig. 3. The essential points of difference are: first, that the section has passed above or below the position of the polar body, thus giving us a clue to its size. As the sections are 0.01 mm thick it follows that the largest diameter of the polar body cannot exceed that measure; second, the material (coagulum?) filling the space between the cytoplasm and the Zona pellucida is uniform in structure, and the large vacuoles have disappeared; third, the size of the three spherical vesicles within the cytoplasm is more nearly equal, suggesting that they have been cut in the axis of the amphiaster. Associated with each lateral sphere, which, as we have already noted, is to be regarded as a centrosphere, may be seen a darkly stained granule, occupying a position, if not quite in the centre, at least near it. ’ These centrospheres are not so precisely defined from the surrounding cytoplasm as in fig. 3, nor are their contents so clear; but these are appearances which may be due to the density of the staining, or to the slight variation in the thickness of the sections.


The nuclear material of the daughter cell, which lies intermediate in position between the two centrospheres, exhibits a granular appearance due to the presence of chromatin grains, some of which are arranged in thread-like fashion.


Historic Disclaimer - information about historic embryology pages 
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Pages where the terms "Historic" (textbooks, papers, people, recommendations) appear on this site, and sections within pages where this disclaimer appears, indicate that the content and scientific understanding are specific to the time of publication. This means that while some scientific descriptions are still accurate, the terminology and interpretation of the developmental mechanisms reflect the understanding at the time of original publication and those of the preceding periods, these terms, interpretations and recommendations may not reflect our current scientific understanding.     (More? Embryology History | Historic Embryology Papers)
Human Ovum Links: Fig 1. Prophase I | Fig 2. | | Fig 3. | Plate 10 | Plate 11 | Plate 12
Online Editor Notes  
  • discus proligerus is an historic term for granulosa cells surrounding the oocyte and forming the cumulus oophorus.
  • meiosis staging cannot be correct as described in text, as human oocyte completes meiosis I at ovulation and only completes meiosis II at fertilization.
  • See also paper by P N Odgers An Early Human Ovum (Thomson) in situ. J. Anat.: 1937, 71(Pt 2);161-168.3 PMID 17104634, describing an early embryo from Prof. Arthur Thomson
Nature Obituary 1935 - Prof. Arthur Thomson (1858 - 1935)
"ON his retirement in 1933, Prof. Arthur Thomson, whose death on February 7 will be widely regretted, had completed a somewhat unusual record of academic service. He was born on March 21, 1858, and for forty-eight years he represented human anatomy at the University of Oxford, first as University lecturer in human anatomy and afterwards as Dr. Lee’s professor of anatomy. After serving an apprenticeship in the famous school of anatomy at Edinburgh under Sir William Turner, Thomson went to Oxford in 1885. Unlike many of his later contemporaries, he did not enjoy the advantage of stepping into a department already equipped for teaching and research. On the contrary, the task fell to him of building up a new department from its very foundations. It will readily be appreciated that Thomson’s energies were fully employed for a number of years in developing the teaching side of his department to a level appropriate to the medical faculty of the University of Oxford, a task which was rendered very laborious at first by the criticism and opposition of some members of the University who were less ready to appreciate the importance of catering for an extensive and detailed medical curriculum."

Nature 135, 295-295 (23 February 1935) | doi:10.1038/135295a0

Modern Notes: oocyte | Category:Oocyte | meiosis


Fertilization Links: fertilization | oocyte | spermatozoa | meiosis | | ovary | testis | menstrual cycle | zona pellucida | zygote | granulosa cell Lecture - Fertilization | 2016 Lecture | mitosis | Lecture - Week 1 and 2 | hydatidiform mole | Assisted Reproductive Technology | | morula | blastocyst | Lecture - Genital Development | Category:Fertilization
Historic Embryology - Fertilization 
1910 Fertilization | 1919 Human Ovum | 1921 The Ovum | 1927 First polar body | 1929 Oocyte Size | 1943 Fertilization | 1944 In vitro fertilization | 1948 In vitro fertilization


Reference

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Cite this page: Hill, M.A. (2024, April 27) Embryology Thomson1919 fig04.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Thomson1919_fig04.jpg

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