File:Nephron development 01.jpg

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Nephron Development

The morphological events and localization of renal progenitors occurring during nephron development in the adult human kidney.

Mesenchymal cells near the tips of the branching ureteric bud undergo epithelial transition and differentiate through a series of forms made up of renal progenitors (red)

  • a - condensed aggregate forms
  • b - renal vesicle forms
  • c - S-shaped body (red), renal progenitors are localised, at this stage podocyte-committed progenitors (red + blue) as well as tubular-committed progenitors (orange) can already be seen.
  • d - mature nephron, renal progenitors (red), podocyte-committed progenitors (red + blue), as well as tubular-committed progenitors (orange) are distributed along the nephron.
  • e - glomerulus, renal progenitors (red) are localized at the urinary pole of the Bowman capsule. Podocyte-committed progenitors (red + blue) localize along the Bowman capsule.


Links: early nephron development | Fetal nephron development | Adult nephron distribution | Renal System Development
Renal Links: renal | Lecture - Renal | Lecture Movie | urinary bladder | Stage 13 | Stage 22 | Fetal | Renal Movies | Stage 22 Movie | renal histology | renal abnormalities | Molecular | Category:Renal
Historic Embryology - Renal  
1905 Uriniferous Tubule Development | 1907 Urogenital images | 1911 Cloaca | 1921 Urogenital Development | 1915 Renal Artery | 1917 Urogenital System | 1925 Horseshoe Kidney | 1926 Embryo 22 Somites | 1930 Mesonephros 10 to 12 weeks | 1931 Horseshoe Kidney | 1932 Renal Absence | 1939 Ureteric Bud Agenesis | 1943 Renal Position

Reference

Romagnani P, Lasagni L & Remuzzi G. (2013). Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nat Rev Nephrol , 9, 137-46. PMID: 23338209 DOI.

Copyright

Reprinted by permission from Macmillan Publishers Ltd: Nature Reviews Nephrology (Romagnani, P. et al. Nat. Rev. Nephrol. 9, 137–146 (2013); published online 22 January 2013; doi:10.1038/nrneph.2012.290), copyright (2013) License Number 3954020439682

Figure 4 resized and relabelled with PMID


Cite this page: Hill, M.A. (2024, April 27) Embryology Nephron development 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Nephron_development_01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current15:05, 22 September 2016Thumbnail for version as of 15:05, 22 September 20161,232 × 960 (240 KB)Z8600021 (talk | contribs)
15:04, 22 September 2016Thumbnail for version as of 15:04, 22 September 20161,318 × 1,477 (414 KB)Z8600021 (talk | contribs)The morphological events and localization of renal progenitors occurring during nephron development in the adult human kidney. Mesenchymal cells near the tips of the branching ureteric bud undergo epithelial transition and differentiate through a ser...

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