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==Illustration of Schwann cell development in the mouse sciatic nerve using electron microscopy==
Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.


During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles
'''Related myelin images:''' [[:File:Mouse-sciatic_nerve_Schwann_cell.jpg|Mouse - sciatic nerve Schwann cell]] | [[:File:Mouse- spinal cord axons.jpg|sciatic nerve]] | [[:File:Mouse-_cerebellum_axons.jpg|cerebellum axons]] | [[:File:Mouse-optic_nerve_axons.jpg|optic nerve]]


(A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination
===Reference===
{{#pmid:17576794}}


(B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.


'''Legend'''
====Copyright====
* Ax - axon
This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
* BL - basal lamina
* SC - Schwann cell


Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg
Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg


==Reference==
{{Footer}}
<pubmed>17576794</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064356 PMC2064356] | [http://jcb.rupress.org/content/177/6/953.long JCB]
 
This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
 
 
[[Category:Glia]] [[Category:Neural]] [[Category:Electron Micrograph]]
[[Category:Glia]] [[Category:Neural]] [[Category:Electron Micrograph]]
[[Category:Schwann cell]]

Latest revision as of 07:22, 26 May 2019

Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.

Related myelin images: Mouse - sciatic nerve Schwann cell | sciatic nerve | cerebellum axons | optic nerve

Reference

Chan JR. (2007). Myelination: all about Rac 'n' roll. J. Cell Biol. , 177, 953-5. PMID: 17576794 DOI.


Copyright

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg


Cite this page: Hill, M.A. (2024, May 20) Embryology Mouse-sciatic nerve Schwann cell.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-sciatic_nerve_Schwann_cell.jpg

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