File:Human Carnegie stage 13 GJA1 expression.jpg

From Embryology

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In situ expression of GJA1 in the human embryo

E Forelimb-level HE transverse section in separate C13 embryo.

F GJA1 antisense probe-hybridized adjacent section. Limb bud, dorsal neural tube and dorsal roots (arrowheads) hybridize more strongly than other tissues, nearly all of which have some basal GJA1 expression.


Abbreviations:

  • aer, apical ectodermal ridge
  • am, amnion
  • cœ, cœlom
  • cv, cardinal vein
  • da, dorsal aorta
  • dC, duct of Cuvier
  • dr/g, dorsal root more or less in plane of ganglion
  • dt, dermatome
  • g, gut
  • la, left atrium
  • lb, limb bud
  • lv, liver bud
  • my, myotome
  • ncc, neural crest cells
  • nd, notochord
  • nt, neural tube
  • pn, pronephros
  • scl, sclerotome
  • spl, splanchnopleura
  • sv, sinus venosus

Bar = 250 µm.

Extracted from Figure 4. http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411/DDN235F4

Links: Carnegie stage 13

Human neural crest cells display molecular and phenotypic hallmarks of stem cells. Thomas S, Thomas M, Wincker P, Babarit C, Xu P, Speer MC, Munnich A, Lyonnet S, Vekemans M, Etchevers HC. Hum Mol Genet. 2008 Nov 1;17(21):3411-25. PMID: 18689800 | Hum Mol Genet.

© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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