File:Human Carnegie stage 13 GJA1 expression.jpg: Difference between revisions

Latest revision as of 13:18, 31 August 2010

In situ expression of GJA1 in the human embryo

E Forelimb-level HE transverse section in separate C13 embryo.

F GJA1 antisense probe-hybridized adjacent section. Limb bud, dorsal neural tube and dorsal roots (arrowheads) hybridize more strongly than other tissues, nearly all of which have some basal GJA1 expression.

GJA1 - gap junction protein, alpha 1, 43kDa encoding connexin43, which is one of 21 connexin proteins in humans. http://ghr.nlm.nih.gov/gene/GJA1

Abbreviations:

aer, apical ectodermal ridge
am, amnion
cœ, cœlom
cv, cardinal vein
da, dorsal aorta
dC, duct of Cuvier
dr/g, plane of dorsal root ganglion

dt, dermatome
g, gut
la, left atrium
lb, limb bud
lv, liver bud
my, myotome
ncc, neural crest cells

nd, notochord
nt, neural tube
pn, pronephros
scl, sclerotome
spl, splanchnopleura
sv, sinus venosus

Bar = 250 µm.

Extracted from Figure 4. http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411/DDN235F4

Links: Carnegie stage 13 | Neural Crest Development

Reference

<pubmed>18689800</pubmed>| Hum Mol Genet.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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@@ Line 5: / Line 5: @@
 '''F''' GJA1 antisense probe-hybridized adjacent section. Limb bud, dorsal neural tube and dorsal roots (arrowheads) hybridize more strongly than other tissues, nearly all of which have some basal GJA1 expression.
+'''GJA1''' - gap junction protein, alpha 1, 43kDa encoding connexin43, which is one of 21 connexin proteins in humans. http://ghr.nlm.nih.gov/gene/GJA1
-Abbreviations:
+===Abbreviations:===
 {|
 |
@@ Line 15: / Line 16: @@
 * da, dorsal aorta
 * dC, duct of Cuvier
-* dr/g, dorsal root more or less in plane of ganglion
+* dr/g, plane of dorsal root ganglion
 |
 * dt, dermatome
@@ Line 37: / Line 38: @@
 Extracted from Figure 4. http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411/DDN235F4
-Links: [[Carnegie stage 13]]
+'''Links:''' [[Carnegie stage 13]] | [[Neural Crest Development]]
-Human neural crest cells display molecular and phenotypic hallmarks of stem cells. Thomas S, Thomas M, Wincker P, Babarit C, Xu P, Speer MC, Munnich A, Lyonnet S, Vekemans M, Etchevers HC. Hum Mol Genet. 2008 Nov 1;17(21):3411-25. [http://www.ncbi.nlm.nih.gov/pubmed/18689800 PMID: 18689800] | [http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]
+==Reference==
+<pubmed>18689800</pubmed>| [http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]
 © 2008 The Author(s)
 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 [[Category:Human Embryo]] [[Category:Carnegie Stage]] [[Category:Carnegie Stage 13]] [[Category:Week 4]] [[Category:Neural]] [[Category:Neural Crest]]