File:Human CS13-15 otic vesicle 01.jpg

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Human Otic Vesicle Carnegie Stages 13 to 15

Laser-microdissection of FFPE-human inner ear slides.

(A) FFPE slides containing embryonic tissues.

(B) Coronal section of a fetus with highlighted regions of interest (dashed black circles, CVG, NC, and OV).

Further images are provided showing tissue before (C, E) and after (D, F) laser-captured microdissection of CVG (dashed white lines in D) and NC tissues (dashed white line in F). Other developmental regions also are highlighted.

CVG: cochlear-vestibular ganglions, OV: otic vesicle, NC: neural crest; GG: geniculate ganglion, G-CVG: geniculate- cochleovestibular ganglions, E: epithelium; and NT: neural tube.

Scale bar = 100 μm (B) and 150 μm (C-F).

Carnegie Stages : 13 32 post ovulatory days, 14 33 post ovulatory days, {{CS15} 35 post ovulatory days

Links: Hearing - Inner Ear Development | Molecular Development - microRNA | Carnegie stage 13 | Carnegie stage 14 | Carnegie stage 15


Chadly DM, Best J, Ran C, Bruska M, Woźniak W, Kempisty B, Schwartz M, LaFleur B, Kerns BJ, Kessler JA & Matsuoka AJ. (2018). Developmental profiling of microRNAs in the human embryonic inner ear. PLoS ONE , 13, e0191452. PMID: 29373586 DOI.


© 2018 Chadly et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Fig 1. Adjusted in size and labelled with PMID.

Cite this page: Hill, M.A. (2024, April 21) Embryology Human CS13-15 otic vesicle 01.jpg. Retrieved from

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current12:19, 6 April 2018Thumbnail for version as of 12:19, 6 April 20181,574 × 1,779 (364 KB)Z8600021 (talk | contribs)
12:12, 6 April 2018Thumbnail for version as of 12:12, 6 April 20181,574 × 2,053 (457 KB)Z8600021 (talk | contribs)* '''Developmental profiling of microRNAs in the human embryonic inner ear'''{{#pmid:29373586|PMID29373586}} "Due to the extreme inaccessibility of fetal human inner ear tissue, defining of the microRNAs (miRNAs) that regulate development of the inner...

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