File:CNS secondary vesicles.jpg

From Embryology

Original file(987 × 562 pixels, file size: 81 KB, MIME type: image/jpeg)

Central Nervous System - Secondary Brain Vesicles

These 5 secondary vesicles developed from the initial 3 primary vesicles of the early neural tube, by division of the forebrain and hindbrain regions.

  1. Telencephalon
  2. Diencephalon
  3. Mesencephalon
  4. Metencephalon
  5. Myelencephalon

The more mature brain with five brain vesicles: the horizontal and lateral views correspond to GD 11.5 in rats and 33 ± 1 in humans.

Links: 3 primary vesicles | 5 secondary vesicles | Neural System Development

Neural Tube Development
Neural Tube Primary Vesicles Secondary Vesicles Adult Structures
week 3 week 4 week 5 adult
neural plate
neural groove
neural tube

prosencephalon (forebrain) telencephalon Rhinencephalon, Amygdala, hippocampus, cerebrum (cortex), hypothalamus‎, pituitary | Basal Ganglia, lateral ventricles
diencephalon epithalamus, thalamus, Subthalamus, pineal, posterior commissure, pretectum, third ventricle
mesencephalon (midbrain) mesencephalon tectum, Cerebral peduncle, cerebral aqueduct, pons
rhombencephalon (hindbrain) metencephalon cerebellum
myelencephalon medulla oblongata, isthmus
spinal cord, pyramidal decussation, central canal


Rice D & Barone S. (2000). Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ. Health Perspect. , 108 Suppl 3, 511-33. PMID: 10852851

Copyright: Reproduced with permission from Environmental Health Perspectives (EHP) is a publication of the U.S. Government. Publication of EHP lies in the public domain and is therefore without copyright.

Cite this page: Hill, M.A. (2024, April 12) Embryology CNS secondary vesicles.jpg. Retrieved from

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

File history

Click on a date/time to view the file as it appeared at that time.

current16:49, 18 May 2017Thumbnail for version as of 16:49, 18 May 2017987 × 562 (81 KB)Z8600021 (talk | contribs)
01:02, 11 August 2009Thumbnail for version as of 01:02, 11 August 2009961 × 462 (58 KB)MarkHill (talk | contribs)CNS primary vesicles cartoon Figure-3CD-PMID10852851.jpg Image Source: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Rice D, Barone S Jr. Environ Health Perspect. 2000 Jun;108 Suppl 3:511-33