File:CNS primary vesicles.jpg

From Embryology

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Central Nervous System - Primary Vesicles

These 3 primary brain vesicles develop initially due to the neural plate being broader at the cranial (brain) end that the narrower caudal (spinal cord) end. When the plate fuses to form a tube, these 3 initial expansions (vesicles) result.

  1. forebrain (prosencephalon)
  2. midbrain (mesencephalon)
  3. hindbrain (rhombencephalon)


  • Development of the three primary brain vesicles on GD 10.5 in rats and 26 ± 1 in humans.
  • Corresponding shading between panels illustrates the earlier origins of different regions from the three original brain vesicles with a horizontal and lateral view, respectively.
  • Later they will develop into the 5 secondary vesicles (telencephalon - diencephalon - mesencephalon - metencephalon - myelencephalon)
Links: 3 primary vesicles | 5 secondary vesicles | Neural System Development


Neural Tube Development
Neural Tube Primary Vesicles Secondary Vesicles Adult Structures
week 3 week 4 week 5 adult
neural plate
neural groove
neural tube

Brain
prosencephalon (forebrain) telencephalon Rhinencephalon, Amygdala, hippocampus, cerebrum (cortex), hypothalamus‎, pituitary | Basal Ganglia, lateral ventricles
diencephalon epithalamus, thalamus, Subthalamus, pineal, posterior commissure, pretectum, third ventricle
mesencephalon (midbrain) mesencephalon tectum, Cerebral peduncle, cerebral aqueduct, pons
rhombencephalon (hindbrain) metencephalon cerebellum
myelencephalon medulla oblongata, isthmus
spinal cord, pyramidal decussation, central canal

Reference

<pubmed>10852851</pubmed>| Environmental Health Perspectives | PMC: 1637807

Original file name: Figure-3AB-PMID10852851.jpg

Copyright: Reproduced with permission from Environmental Health Perspectives (EHP) is a publication of the U.S. Government. Publication of EHP lies in the public domain and is therefore without copyright.



Cite this page: Hill, M.A. (2024, April 12) Embryology CNS primary vesicles.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:CNS_primary_vesicles.jpg

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

Cite this page: Hill, M.A. (2024, April 12) Embryology CNS primary vesicles.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:CNS_primary_vesicles.jpg

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

File history

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current16:48, 18 May 2017Thumbnail for version as of 16:48, 18 May 2017987 × 562 (49 KB)Z8600021 (talk | contribs)
16:18, 5 April 2017Thumbnail for version as of 16:18, 5 April 2017961 × 462 (45 KB)Z8600021 (talk | contribs)
01:01, 11 August 2009Thumbnail for version as of 01:01, 11 August 2009961 × 462 (50 KB)MarkHill (talk | contribs)CNS primary vesicles cartoon Figure-3AB-PMID10852851.jpg Image Source: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Rice D, Barone S Jr. Environ Health Perspect. 2000 Jun;108 Suppl 3:511-33