|Embryology - 24 May 2019 Expand to Translate|
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The uterine gland or endometrial gland is a simple tubular gland formed by invagination of the uterine endometrium. The uterine epithelium is described as a columnar epithelium of ciliated cells and secretory cells.
The glands extend into the underlying thick vascular stromal layer. The glands line the uterus body and change in appearance and secretion during the menstrual cycle. The glands secretions function to provide the initial nutritional support of the conceptus and may have a role in maintaining adhesion.
Some Recent Findings
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
<pubmed limit=5>Uterine Gland</pubmed>
Uterine Gland Histology During the Menstrual Cycle
|Uterine gland proliferative phase||Uterine gland secretory phase|
Menstrual Cycle Histology
The different stages of the menstrual cycle can be monitored by the cellular appearance of vaginal smears Menstrual Cycle - Histology.
A more invasive technique is dilate and curettage (DnC), which allows sampling of the functional layer of the uterine endometrium Menstrual Cycle - Histology.
Decidualization is the process of converting endometrial stromal cells into decimal cells and requires at least 8–10 days of hormone stimulation.
- initiated during the mid-secretory phase of the menstrual cycle
- in response to elevated progesterone levels
- acts mainly through progesterone receptor (PR) PR-A (other isoform is PR-B)
PMID: 21546446 Prokineticin 1 (PROK1) signalling via prokineticin receptor 1 (PROKR1) regulates Dickkopf 1 (DKK1) expression, a negative regulator of canonical Wnt signaling.
- Links: Placenta - Maternal Decidua
Term used to describe in early placenta development the intital transfer of nutrition from maternal to embryo (histiotrophic nutrition) compared to later blood-borne nutrition (hemotrophic nutrition). Histotroph is the nutritional material accumulated in spaces between the maternal and fetal tissues, derived from the maternal endometrium and the uterine glands. This nutritional material is absorbed by phagocytosis initially by blastocyst trophectoderm and then by trophoblast of the placenta. in later placental development nutrition is by the exchange of blood-borne materials between the maternal and fetal circulations, hemotrophic nutrition.
- Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Walker HK, Hall WD, Hurst JW, editors. Boston: Butterworths; 1990. Birth Control | Figure 174.1 A 28-day menstrual cycle. Not all cycles are 28 days long. It is the phase before ovulation that varies in length.
- Endocrinology: An Integrated Approach. Nussey S, Whitehead S. Oxford: BIOS Scientific Publishers; 2001. Box 6.42 The human menstrual cycle | Box 6.43 Feedback control of the hypothalamo-pituitary-ovarian axis
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Cite this page: Hill, M.A. (2019, May 24) Embryology Uterine Gland. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Uterine_Gland
- © Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G