File:CNS primary vesicles.jpg

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Central Nervous System - Primary Vesicles

These 3 primary brain vesicles develop initially due to the neural plate being broader at the cranial (brain) end that the narrower caudal (spinal cord) end. When the plate fuses to form a tube, these 3 initial expansions (vesicles) result.

  1. forebrain (prosencephalon)
  2. midbrain (mesencephalon)
  3. hindbrain (rhombencephalon)


  • Development of the three primary brain vesicles on GD 10.5 in rats and 26 ± 1 in humans.
  • Corresponding shading between panels illustrates the earlier origins of different regions from the three original brain vesicles with a horizontal and lateral view, respectively.
  • Later they will develop into the 5 secondary vesicles (telencephalon - diencephalon - mesencephalon - metencephalon - myelencephalon)
Links: 3 primary vesicles | 5 secondary vesicles | Neural System Development


Neural Tube Development
Neural Tube Primary Vesicles Secondary Vesicles Adult Structures
week 3 week 4 week 5 adult
neural plate
neural groove
neural tube

Brain
prosencephalon telencephalon Rhinencephalon, Amygdala, Hippocampus, Cerebrum (Cortex), Hypothalamus, Pituitary | Basal Ganglia, lateral ventricles
Diencephalon Epithalamus, Thalamus, Subthalamus, Pineal, third ventricle
mesencephalon mesencephalon Tectum, Cerebral peduncle, Pretectum, cerebral aqueduct
rhombencephalon metencephalon pons, cerebellum
myelencephalon medulla oblongata
spinal cord

Reference

<pubmed>10852851</pubmed>| Environmental Health Perspectives | PMC: 1637807

Original file name: Figure-3AB-PMID10852851.jpg

Copyright: Reproduced with permission from Environmental Health Perspectives (EHP) is a publication of the U.S. Government. Publication of EHP lies in the public domain and is therefore without copyright.



Cite this page: Hill, M.A. (2019, May 25) Embryology CNS primary vesicles.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:CNS_primary_vesicles.jpg

What Links Here?
© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

Cite this page: Hill, M.A. (2019, May 25) Embryology CNS primary vesicles.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:CNS_primary_vesicles.jpg

What Links Here?
© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current16:48, 18 May 2017Thumbnail for version as of 16:48, 18 May 2017987 × 562 (49 KB)Z8600021 (talk | contribs)
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01:01, 11 August 2009Thumbnail for version as of 01:01, 11 August 2009961 × 462 (50 KB)MarkHill (talk | contribs)CNS primary vesicles cartoon Figure-3AB-PMID10852851.jpg Image Source: Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Rice D, Barone S Jr. Environ Health Perspect. 2000 Jun;108 Suppl 3:511-33
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