ANAT2341 Lab 11 - Heart

From Embryology
Lab 11: Introduction | Heart | Heart Abnormalities | Individual Assessment
Group Projects - Assessor Final review before next week submission. Signalling: 1 Wnt | 2 Notch | 3 FGF Receptor | 4 Hedgehog | 5 T-box | 6 TGF-Beta


Advanced Heart Development Timeline.jpg

Heart1 atrium.gif

Cardiovascular Movies

These simple cartoons show, almost in developmental sequence, aspects of cardiac development. Each linked page is supported by simple descriptions of events shown in the movie (Note - Quicktime and Flash links are 2 versions of the same movie, the Flash movies will not play on iPads or iPhones).

Week3 folding icon.jpg
 ‎‎Week 3
Page | Play
Whole Embryo Folding

The animation shows how the folding of the whole embryo in week 3-4 (GA week 5-6) brings the cardiac region into its anatomical location.

Heart1 looping icon.jpg
 ‎‎Heart Looping
Page | Play
Heart Looping

The early heart tube buckles and folds as it grows in length, forming the initial shape of the future heart.

Heart1 realign icon.jpg
 ‎‎Heart Realign
Page | Play
Ventricular Growth

As the ventricular region grows there is a realignment of the ventricles in the developing heart tube.

Heart1 atrium icon.jpg
 ‎‎Atrial Septation
Page | Play
Atrial Septation

The division of the atria occurs by the growth of two separate overlapping septa in the embryonic period. Note that both septa are not complete and allow blood to pass between the two atria during the entire prenatal period (embryonic and fetal).

Heart1 ventricle icon.jpg
 ‎‎Outflow Septation
Page | Play
Outflow Septation

The ventricles initially separate by growth of the inferior muscular wall. Later the superior region separates by outgrowth of membranous regions that extend into the outflow tract. This third and final septation, leads to a separation of the pulmonary and aortic arch circulations. (Note that a shunt, the ductus arteriosus will persist through the entire prenatal period (embryonic and fetal).


The historic movies below include an audio commentary of cardiac development events (note the audio is unfortunately quite poor).

Historic Heart Development Movies (Historic Disclaimer)
Heart historic 001 icon.jpg
 ‎‎Anatomy
Page | Play
Heart historic 002 icon.jpg
 ‎‎Week 3
Page | Play
Heart historic 003 icon.jpg
 ‎‎Week 3-5
Page | Play
Heart historic 004 icon.jpg
 ‎‎Week 4-11
Page | Play
Heart historic 005 icon.jpg
 ‎‎Embryo overview
Page | Play
Heart historic 006 icon.jpg
 ‎‎AV Septation
Page | Play
Heart historic 007 icon.jpg
 ‎‎Outflow Septation
Page | Play
Heart historic 008 icon.jpg
 ‎‎Valve+Overview
Page | Play

Cardiac Embryology Tutorial

Next work through the online Cardiac Embryology Tutorial.

Human embryo stage 10 heart tube
Cardiac Embryology     Begin Basic     Begin Intermediate     Begin Advanced  


This website is an educational resource designed to teach human cardiac embryology and is a Medicine ILP project carried out by Phoebe Norville. Heart development represents an important area of both embryological and clinical studies, predominantly due to the high incidence of congenital heart disease in the community. Therefore this website aims to teach cardiac embryology to students of all ages with varying degrees of knowledge in the area. The module contains three different levels:

  • Basic - begin here if you are new to heart embryology (high school level)
  • Intermediate - begin here if you have some background in heart embryology (university level)
  • Advanced - begin here after you have completed the earlier levels and have a good background in heart embryology (university level)

Your initial knowledge level determines your start level. Each level is then divided into a sequence of units/pages that roughly correspond to the sequence of heart development. The more detailed, the more pages; basic level has only 3 units, intermediate has 7 units, and the advanced module has 9 units. You can work through each level in sequence or jump to a more detailed level within each unit.

Navigation

Each unit also has two sets of navigation panels and a timeline, to help work through the cardiac embryology modules.

Top navigation panel

This panel allows you to easily move between pages within the same level or to jump to the beginning of a different level; green is the basic module, yellow the intermediate, and red the advanced.

Navigation bar 1.jpg
Bottom navigation panel

This panel allows you to easily move through the information sequentially as well as moving to the same content in a different level of complexity.

Navigation bar 2.jpg
Timelines

A timeline will appear at the top of each page to help you understand the order and context of the events occurring in cardiac embryology.

Basic Heart Development Timeline.jpg


Many of the concepts taught in embryology are best represented with animations or diagrams. The animations in this module are played using Adobe Flash Player. Most of the pictures appear in the units as thumbnails. To see the images more clearly simply click on the picture which will take you to the original-sized version. To return to the module simply click the back button in your browser window.

Basic module

Basicicon.jpg
  1. The Primitive Heart Tube
  2. Divisions of the Embryonic Heart
  3. Vascular Connections to the Embryonic Heart

Intermediate module

Intermediateicon.jpg
  1. Primordial Heart Tube
  2. Looping of the Heart Tube
  3. Atrial and Ventricular Septation
  4. Development of the Outflow Tract
  5. Development of Heart Valves
  6. Abnormalities of Cardiac Development
  7. Overview of Vascular Development

Advanced module

Advancedicon.jpg
  1. Early Embryonic Heart Fields
  2. The Endocardial Heart Tubes
  3. Cardiac Looping
  4. Cardiac Septation
  5. Outflow Tract Development
  6. Valve Development
  7. Development of the Cardiac Conduction System
  8. Developmental Abnormalities
  9. Molecular Control of Development


Cardiac Embryology     Begin Basic     Begin Intermediate     Begin Advanced  


Lab 11: Introduction | Heart | Heart Abnormalities | Individual Assessment
Group Projects - Assessor Final review before next week submission. Signalling: 1 Wnt | 2 Notch | 3 FGF Receptor | 4 Hedgehog | 5 T-box | 6 TGF-Beta

Glossary Links

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Cite this page: Hill, M.A. (2019, September 19) Embryology ANAT2341 Lab 11 - Heart. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/ANAT2341_Lab_11_-_Heart

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G