Template:Main Page News: Difference between revisions

Revision as of 16:43, 1 August 2016

News - Dolly's sisters live on!

PMID 27459299 This recent report showed that 13 cloned sheep generated from the same cell line that produced "Dolly" and have survived much longer, appear to have health measurements within the normal ranges.

Links: Somatic Cell Nuclear Transfer | Sheep Development

Older News Articles - Thalidomide in Zebrafish | Human pancreas stem cells | Oral contraceptive no risk of major birth defects | Maternal Malaria Neurovascular Development Effects | Oocyte/Spermatozoa fate decision Rubella eliminated in the Americas | Three-person embryos | 2014 Nobel Prize in Medicine - Neural Development | Hippocampus Development | WHO - Trends in Maternal Mortality 1990 to 2013 - Statistics - Maternal Mortality | WHO polio - Polio Virus | Trisomy 21 - Genome-wide Effects

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-| <span style="font-size:150%">'''News - Thalidomide Molecular Mechanism shown in Zebrafish</span>
+| <span style="font-size:150%">'''News - Dolly's sisters live on!</span>
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-| valign=top|[[File:Thalidomide destabilizes CD147.jpg|300px|left|alt=Thalidomide destabilizes CD147|link=Abnormal Development - Thalidomide]]
+| valign=top|[[File:Sheep 8-year old clones.jpg|300px|left|alt=Four 8-year old Finn-Dorset clones|link=Somatic Cell Nuclear Transfer]]
-PMID 27294876 | [http://www.nature.com/nm/journal/vaop/ncurrent/full/nm.4128.html Nat Med.]
+PMID 27459299 This recent report showed that 13 cloned sheep generated from the same cell line that produced "Dolly" and have survived much longer, appear to have health measurements within the normal ranges.
-Thalidomide (and derivatives lenalidomide and pomalidomide) are treatments for hematologic malignancies, [http://www.omim.org/entry/254500 multiple myeloma] (MM) and del(5q) [http://www.omim.org/entry/614286 myelodysplastic syndrome] (MDS).  Cereblon (CRBN) is the primary target for both the anticancer and teratogenic effects, and it promotes the maturation of CD147 ([[Abnormal Development - Thalidomide#CD147 (Basigin)|also known as Basigin]]) a member of the immunoglobulin superfamily).
+:'''Links:''' [[Somatic Cell Nuclear Transfer]] | [[Sheep Development]]
-Zebrafish knockdown of CD147 was shown to match the teratogenic effects of thalidomide exposure.
-:'''Links:''' [[Abnormal Development - Thalidomide]] | [[Zebrafish Development]]
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-:[[Template_talk:Main_Page_News|Older News Articles]] - [[Template_talk:Main_Page_News#March|Human pancreas stem cells show glycemic control in mice]] | [[Template_talk:Main_Page_News#January|Oral contraceptive no risk of major birth defects]] | [[Template_talk:Main_Page_News#September|Maternal Malaria Neurovascular Development Effects]] | [[Template_talk:Main_Page_News#June|Oocyte/Spermatozoa fate decision]] [[Template_talk:Main_Page_News#April|Rubella eliminated in the Americas]] | [[Template_talk:Main_Page_News#February|Three-person embryos]] | 2014 Nobel Prize in Medicine -  [http://www.nobelprize.org/nobel_prizes/medicine/laureates/2014/press.html Neural Development] | [[Neural_-_Hippocampus_Development|Hippocampus Development]] | WHO - Trends in Maternal Mortality 1990 to 2013 - [[Statistics - Maternal Mortality]] | WHO polio - [[Abnormal Development - Polio Virus|Polio Virus]] | [[Template_talk:Main_Page_News#March|Trisomy 21 - Genome-wide Effects]]
+:[[Template_talk:Main_Page_News|Older News Articles]] - [[Template_talk:Main_Page_News#June|Thalidomide in Zebrafish]]  | [[Template_talk:Main_Page_News#March|Human pancreas stem cells]] | [[Template_talk:Main_Page_News#January|Oral contraceptive no risk of major birth defects]] | [[Template_talk:Main_Page_News#September|Maternal Malaria Neurovascular Development Effects]] | [[Template_talk:Main_Page_News#June|Oocyte/Spermatozoa fate decision]] [[Template_talk:Main_Page_News#April|Rubella eliminated in the Americas]] | [[Template_talk:Main_Page_News#February|Three-person embryos]] | 2014 Nobel Prize in Medicine -  [http://www.nobelprize.org/nobel_prizes/medicine/laureates/2014/press.html Neural Development] | [[Neural_-_Hippocampus_Development|Hippocampus Development]] | WHO - Trends in Maternal Mortality 1990 to 2013 - [[Statistics - Maternal Mortality]] | WHO polio - [[Abnormal Development - Polio Virus|Polio Virus]] | [[Template_talk:Main_Page_News#March|Trisomy 21 - Genome-wide Effects]]
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