Neural System - Abnormalities
Introduction
There are many different congenital and maternally derived abnormalities associated with the nervous system. There are potentially 1000's of neurological abnormalities that could be listed on this page, therefore this current page is only a very brief introduction to some neural abnormalities.
Some Recent Findings
Neural Tube Closure
Dysraphism is the term often used to describe the defective fusion of the neural folds. The position and degree of failure of fusion will result in either embryonic death or a range of different neural defects. The way (mode) in which the human neural tube fuses has been a source of contention. In humans, fusion appears to initiate at multiple sites but the mode is different from that found in many animal species used in developmental studies.
Human Embryonic Death:
5 weeks with total failure of fusion.
6.5 weeks with opening over the rhombencephalon.
survive beyond 7 weeks with a defect at the frontal and parietal regions.
(Data: Nakatsu etal, 2000[1]
References
- ↑ Nakatsu T, Uwabe C, Shiota K. Neural tube closure in humans initiates at multiple sites: evidence from human embryos and implications for the pathogenesis of neural tube defects. Anat Embryol (Berl). 2000 Jun;201(6):455-66.)
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Cite this page: Hill, M.A. (2024, May 13) Embryology Neural System - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_System_-_Abnormalities
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G