Mouse Lymph Node Movie 4
Embryology - 10 Dec 2023    Expand to Translate
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| <html5media height="400" width="400">File:Mouse_adult_lymph_node_04.mp4</html5media> | 
Adult Mouse Lymph Node - T cells within the medullary sinus. Single T cell traversing the sinus endothelial barrier. |
Movies show lymphocyte traffic through adult lymph nodes. Cells were isolated from spleens and lymph nodes of BALB/c mice.
| Adult Mouse Lymphocyte Motility | |||||||||||||||
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| Transendothelial migration |
T cell zone | Medullary sinus | Sinus endothelial barrier | ||||||||||||
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| Bi-directional traffic | Cross the sinus endothelial barrier |
T and B cell motility | T and B cell coupling | ||||||||||||
| Mouse Immune Movies: Transendothelial migration | T cell zone | Medullary sinus | Sinus endothelial barrier | Bi-directional traffic | cross the sinus endothelial barrier | T and B cell motility | T and B cell coupling | T cell Elimination | Immune System Development | Mouse Development | |||||||||||||||
- Links: Immune System Development | Lymph Node Development | Lecture - Lymphatic Structure and Organs
References
Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E, Wong CH, Parker I & Cahalan MD. (2005). Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat. Immunol. , 6, 1228-35. PMID: 16273098 DOI.
Cahalan MD & Parker I. (2008). Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu. Rev. Immunol. , 26, 585-626. PMID: 18173372 DOI.
Movie Source
Michael D. Cahalan, Professor and Chair, Department of Physiology and Biophysics, University of California, Irvine. Lab Two-photon imaging movies reproduced with permission of Prof. Cahalan.
Glossary Links: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Movies
Cite this page: Hill, M.A. (2023, December 10) Embryology Mouse Lymph Node Movie 4. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Mouse_Lymph_Node_Movie_4
- © Dr Mark Hill 2023, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
