File:Somitogenesis 01 icon.jpg

Hes1 in Presomitic Mesoderm

Selected frame from realtime expression of Hes1 in presomitic mesoderm in the mouse embryo showing rostro-caudal axis.

"Real-time images of the PSM of an embryonic day (E)10.5 Hes1-Ub1-Luc embryo. Images were taken by 20-min exposure and binning of pixels 4 × 4 over a period of 15 h. Oscillation was propagated from the caudal end to S0 in the PSM."

Movie Source: Masamizu Y, Ohtsuka T, Takashima Y, Nagahara H, Takenaka Y, Yoshikawa K, Okamura H, Kageyama R. Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1313-8. Copyright (2006) National Academy of Sciences, U.S.A PMID: 16432209 | PNAS | PNAS Movies | Movie 2

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Proceedings National Academy of Sciences (PNAS) Liberalization of PNAS copyright policy: Noncommercial use freely allowed Note original Author should be contacted for permission to reuse for Educational purposes. See also PNAS Author Rights and Permission FAQs

Cozzarelli NR, Fulton KR, Sullenberger DM. Liberalization of PNAS copyright policy: noncommercial use freely allowed. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12399. PMID15314225 "Our guiding principle is that, while PNAS retains copyright, anyone can make noncommercial use of work in PNAS without asking our permission, provided that the original source is cited."

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