Somitogenesis Molecular Movie

Embryology - 11 Dec 2023 Expand to Translate
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<html5media height="360" width="300">File:somitogenesis 001.mp4</html5media>

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Molecular Patterning of Presomitic Mesoderm

This imaging of the early mouse embryo shows the localised expression in mesoderm of the transcription factor Hes1 that cycles coordinately preceding the formation of new somite pairs in a rostro-cauldal direction.

Realtime expression of Hes1 in presomitic mesoderm (PSM) in the mouse embryo. Embryonic day E10.5 Hes1-Ub1-Luc embryo. Images were taken by 20-min exposure and binning of pixels 4 × 4 over a period of 15 h. Oscillation was propagated from the caudal end to S0 in the PSM."

Links: MP4 version | Somitogenesis | Mesoderm | Molecular Development

Model for Sprouty4 and FGF in mesoderm segmentation

About Hes1

Hairy/Enhancer of Split (Drosophila), Homolog of, 1; HES1
basic helix-loop-helix (bHLH) protein
transcription factor

Reference

<pubmed>16432209</pubmed>| PNAS

Copyright

Proceedings National Academy of Sciences (PNAS) Liberalization of PNAS copyright policy: Noncommercial use freely allowed Note original Author should be contacted for permission to reuse for Educational purposes. See also PNAS Author Rights and Permission FAQs

Cozzarelli NR, Fulton KR, Sullenberger DM. Liberalization of PNAS copyright policy: noncommercial use freely allowed. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12399. PMID15314225 "Our guiding principle is that, while PNAS retains copyright, anyone can make noncommercial use of work in PNAS without asking our permission, provided that the original source is cited."

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Cite this page: Hill, M.A. (2023, December 11) Embryology Somitogenesis Molecular Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Somitogenesis_Molecular_Movie

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