File:Mouse somitogenesis genes.jpg

Gene Regulation During Mouse Somitogenesis

Position of a gene symbol on the plot reflects time of peak expression (angle; clockwise) and the mean expression level (genes with high expression level are closer to the center).

• Arrows represent the known causation (green arrows connect genes in the causation direction matching those found in the literature and red arrows are in the reverse causation order.

• Dot links are between genes too distant to indicate direction of causation).

• Solid black arcs represent the estimated timing accuracy for each gene. Causation directions are compiled from literature.

• Genes are color-coded according to their known pathway association:

• • green - Notch

• • magenta - Fgf

• • purple - Wnt

• dashed strokes are used for genes previously not reported as cyclic.

Links: somitogenesis | Notch | FGF | Wnt | Molecular Development

Reference

Fongang B & Kudlicki A. (2013). The precise timeline of transcriptional regulation reveals causation in mouse somitogenesis network. BMC Dev. Biol. , 13, 42. PMID: 24304493 DOI.

Copyright

© 2013 Fongang and Kudlicki; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figure 3. Gene regulation during mouse somitogenesis.

Cite this page: Hill, M.A. (2024, April 27) Embryology Mouse somitogenesis genes.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse_somitogenesis_genes.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G