File:Mouse somitogenesis genes.jpg

From Embryology

Original file(828 × 800 pixels, file size: 119 KB, MIME type: image/jpeg)

Gene Regulation During Mouse Somitogenesis

Position of a gene symbol on the plot reflects time of peak expression (angle; clockwise) and the mean expression level (genes with high expression level are closer to the center).

  • Arrows represent the known causation (green arrows connect genes in the causation direction matching those found in the literature and red arrows are in the reverse causation order.
  • Dot links are between genes too distant to indicate direction of causation).
  • Solid black arcs represent the estimated timing accuracy for each gene. Causation directions are compiled from literature.
  • Genes are color-coded according to their known pathway association:
    • green - Notch
    • magenta - Fgf
    • purple - Wnt
  • dashed strokes are used for genes previously not reported as cyclic.


Links: somitogenesis | Notch | FGF | Wnt | Molecular Development


Reference

Fongang B & Kudlicki A. (2013). The precise timeline of transcriptional regulation reveals causation in mouse somitogenesis network. BMC Dev. Biol. , 13, 42. PMID: 24304493 DOI.

Copyright

© 2013 Fongang and Kudlicki; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Figure 3. Gene regulation during mouse somitogenesis.


Cite this page: Hill, M.A. (2024, May 26) Embryology Mouse somitogenesis genes.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse_somitogenesis_genes.jpg

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current19:42, 28 December 2013Thumbnail for version as of 19:42, 28 December 2013828 × 800 (119 KB)Z8600021 (talk | contribs)==Gene Regulation During Mouse Somitogenesis== Position of a gene symbol on the plot reflects time of peak expression (angle; clockwise) and the mean expression level (genes with high expression level are closer to the center). Arrows represent the kn...

Metadata