File:Mouse-sciatic nerve Schwann cell.jpg

Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.

Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg

Reference

<pubmed>17576794</pubmed>| PMC2064356 | JCB

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