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==Illustration of Schwann cell development in the mouse sciatic nerve using electron microscopy==
Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.


During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles
Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg


'''A''' Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination
'''Related myelin images:''' [[:File:Mouse-sciatic_nerve_Schwann_cell.jpg|Mouse - sciatic nerve Schwann cell]] | [[:File:Mouse-sciatic nerve Schwann cell.jpg|sciatic nerve]] | [[:File:Mouse-_cerebellum_axons.jpg|cerebellum axons]] | [[:File:Mouse-optic_nerve_axons.jpg|optic nerve]]
 
'''B''' Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.
 
'''Legend'''
* Ax - axon
* BL - basal lamina
* SC - Schwann cell
 
Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg


==Reference==
==Reference==

Revision as of 13:32, 24 September 2010

Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.

Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg

Related myelin images: Mouse - sciatic nerve Schwann cell | sciatic nerve | cerebellum axons | optic nerve

Reference

<pubmed>17576794</pubmed>| PMC2064356 | JCB

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current12:50, 24 September 2010Thumbnail for version as of 12:50, 24 September 2010957 × 1,050 (339 KB)S8600021 (talk | contribs) Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, ou

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