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(Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, out)
 
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Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.
Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.


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==Reference==
==Reference==
<pubmed>17576794</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064356 PMC2064356] | [http://jcb.rupress.org/content/177/6/953.long JCB]
<pubmed>17576794</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064356 PMC2064356] | [http://jcb.rupress.org/content/177/6/953.long JCB]
This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
[[Category:Glia]] [[Category:Neural]]

Revision as of 12:52, 24 September 2010

Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.

Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg

Reference

<pubmed>17576794</pubmed>| PMC2064356 | JCB

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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