File:Mouse-sciatic nerve Schwann cell.jpg

Illustration of Schwann cell (SC) development in the mouse sciatic nerve using electron microscopy. During peripheral nerve development, Schwann cells proliferate, migrate, and ensheath axon (Ax) bundles (A). Schwann cells organize a basal lamina (BL, outlined in blue), which completely surrounds each individual cell and the associated axon(s). Upon receiving the appropriate signals from the local environment, Schwann cells will sort through the axon bundle, isolate an individual axon, and then initiate myelination (B). Bottom panels are schematic representations of the electron micrographs in the top panels, and represent radial sorting, initiation, and myelination of a single axon.

Related myelin images: Mouse - sciatic nerve Schwann cell | sciatic nerve | cerebellum axons | optic nerve

Reference

Chan JR. (2007). Myelination: all about Rac 'n' roll. J. Cell Biol. , 177, 953-5. PMID: 17576794 DOI.

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Figure 1. http://jcb.rupress.org/content/177/6/953/F1.large.jpg

Cite this page: Hill, M.A. (2024, April 27) Embryology Mouse-sciatic nerve Schwann cell.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-sciatic_nerve_Schwann_cell.jpg

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