File:Mouse- embryonic stem cell signaling regulation.jpg

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Mouse - Embryonic Etem cell regulation

Core transcriptional regulatory circuitry in pluripotent mouse ESCs.

Recent papers have demonstrated a role for Krüppel-like transcription factors 2, 4 and 5 in the control of mouse embryonic stem cell pluripotency. However, it is not clear whether each factor has a unique role or whether they are functionally redundant. A paper by Parisi and colleagues in BMC Biology now sheds light on the mechanism by which Klf5 regulates pluripotency.

Links: stem cells | SOX

Reference

Bourillot PY & Savatier P. (2010). Krüppel-like transcription factors and control of pluripotency. BMC Biol. , 8, 125. PMID: 20875146 DOI.

Copyright

© 2010 Bourillot and Savatier; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

See article BMC Biol.

Original file name: Figure 1. 1741-7007-8-125-1.jpg



Cite this page: Hill, M.A. (2019, December 15) Embryology Mouse- embryonic stem cell signaling regulation.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-_embryonic_stem_cell_signaling_regulation.jpg

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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