File:Eukaryotic mitochondrial genomes.jpg

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Origin and Conservation of the Mitochondrial System

  • Orthology was used to identify functional processes in yeast that originate from bacteria and are conserved to humans.
  • Modules of five or more proteins are shown as single nodes at the circumference of the circle and the degree of evidence connecting modules is shown by lines in different gray tone.
  • The connection between modules is calculated as the average of the STRING interaction scores for all protein-pairs. Modules are distributed according to their localization.
  • Color in the inner rings reflects for each module the percentage of proteins that have proteobacterial orthology (red) or human orthology (blue).
  • The number of proteobacterial orthologs is also indicated.


Links: mitochondria | genetics | genetic abnormalities | 16569 bp Homo sapiens mitochondrion | Mitochondrial DNA Deletion Syndromes

Reference

Perocchi F, Jensen LJ, Gagneur J, Ahting U, von Mering C, Bork P, Prokisch H & Steinmetz LM. (2006). Assessing systems properties of yeast mitochondria through an interaction map of the organelle. PLoS Genet. , 2, e170. PMID: 17054397 DOI.

Copyright

© 2006 Perocchi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1617129&tool=pmcentrez



Cite this page: Hill, M.A. (2024, April 15) Embryology Eukaryotic mitochondrial genomes.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Eukaryotic_mitochondrial_genomes.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current10:43, 23 June 2011Thumbnail for version as of 10:43, 23 June 2011794 × 782 (117 KB)S8600021 (talk | contribs)==Origin and Conservation of the Mitochondrial System== Orthology was used to identify functional processes in yeast that originate from bacteria and are conserved to humans. Modules of five or more proteins are shown as single nodes at the circumference

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