File:Corpus luteum.jpg

From Embryology

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Ovary - Corpus Luteum

Histology image shows the corpus luteum (CL, yellow body)

  • The ovulating follicle forms initially the corpus hemorrhagicum and then corpus luteum.
  • Corpus luteum (CL, yellow body) outer layer consisting of theca lutein cells and more centrally the granulosa lutein cells.
  • Corpus luteum core is initially filled with a blood clot, following ovulation, and is the invaded by connective tissue.

Theca lutein cells and granulosa lutein cells work together in the production of ovarian hormones that support the initial pregnancy. Lack of implantation and associated hCG will lead to this structure not producing hormones and forming the corpus albicans (white body).

Theca Lutein Cells

  • darker stained cells.
  • derived from the theca interna of the original follicle.
  • lack microvilli on the surface.
  • lack the aromatase enzyme.
  • produce androgens for the granulosa lutein cells to convert.

Granulosa Lutein Cells

  • lighter stained cells.
  • derived from the granulosa cells of the original follicle.
  • contain aromatase enzyme.
  • produce estrogen and progesterone from the androgens produced by the theca lutein cells.

Corpus Luteum Links: anatomy overview | image - histology overview | image - Layers granulosa and theca | image - Layers detail granulosa and theca | image - low power label | image - high power label | image - low power | image - high power | image - corpus albicans | theca and granulosa lutein cells | Granulosa cell | corpus luteum | granulosa lutein cells | theca lutein cells | corpus albicans | ovary | menstrual cycle
  Historic Papers: 1969 corpus luteum ultrastructure 1 | 1969 corpus luteum ultrastructure 2

Links: Histology | Histology Stains | Blue Histology images copyright Lutz Slomianka 1998-2009. The literary and artistic works on the original Blue Histology website may be reproduced, adapted, published and distributed for non-commercial purposes. See also the page Histology Stains.

Cite this page: Hill, M.A. (2024, June 19) Embryology Corpus luteum.jpg. Retrieved from

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

Histology image H&E high power Clu01he.jpg

File history

Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan

current16:58, 6 May 2012Thumbnail for version as of 16:58, 6 May 2012450 × 600 (94 KB)Z8600021 (talk | contribs)
10:14, 3 August 2009Thumbnail for version as of 10:14, 3 August 2009300 × 400 (55 KB)MarkHill (talk | contribs)Corpus luteum Histology image H&E low power Image Source: Lutz Slomianka, UWA Blue Histology Clu01he.jpg