File:Adrenal and gonad early development.jpg: Difference between revisions

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Adrenal and Gonad Early Development

The key events of molecular development of steroidogenic tissues in mice are shown in this cartoon. Dax-1 function in sex determination is still unclear.

male sex - SRY, SOX9, SF-1, Dax-1
female sex - Wnt4, Dax-1

Steroidogenic Factor 1

53 kDa protein called Ad4BP (Adrenal 4 Binding Protein) or SF-1 (Steroidogenic Factor 1)
classical DNA-binding domain (DBD) characterized by two Cys2-Cys2 zinc fingers in the N-terminal region
SF-1 binds DNA as a monomer
high homology with the drosophila Ftz-F1 transcription factor that controls fushi tarazu homeotic gene expression

Reference

<pubmed>14594453</pubmed>| Nucl Recept.

Copyright

© 2003 Val et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. Val et al. Nuclear Receptor 2003 1:8 doi:10.1186/1478-1336-1-8 http://www.nuclear-receptor.com/content/1/1/8

Original file name: Figure 2. 1478-1336-1-8-2-l.jpg http://www.nuclear-receptor.com/content/1/1/8/figure/F2 (cartoon cropped from full image)

Cite this page: Hill, M.A. (2024, May 2) Embryology Adrenal and gonad early development.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Adrenal_and_gonad_early_development.jpg

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	15:00, 28 May 2011		700 × 397 (50 KB)	S8600021 (talk \| contribs)	==Adrenal and Gonad Early Development== The key events of steroidogenic tissues development in mice are shown. Molecular players in male sex (SRY, SOX9, SF-1, Dax-1) and female sex determination (Wnt4, Dax-1) are shown. Dax-1 function in sex determinatio

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@@ Line 1: / Line 1: @@
 ==Adrenal and Gonad Early Development==
-The key events of steroidogenic tissues development in mice are shown. Molecular players in male sex (SRY, SOX9, SF-1, Dax-1) and female sex determination (Wnt4, Dax-1) are shown. Dax-1 function in sex determination is still unclear.
+The key events of molecular development of steroidogenic tissues in mice are shown in this cartoon. Dax-1 function in sex determination is still unclear.
+* male sex - SRY, SOX9, SF-1, Dax-1
+* female sex - Wnt4, Dax-1
 ===Steroidogenic Factor 1===
@@ Line 9: / Line 13: @@
 * high homology with the drosophila Ftz-F1 transcription factor that controls fushi tarazu homeotic gene expression
-Original file name: Figure 2.  1478-1336-1-8-2-l.jpg http://www.nuclear-receptor.com/content/1/1/8/figure/F2 (cartoon cropped from full image)
-==Reference==
+===Reference===
 <pubmed>14594453</pubmed>| [http://www.nuclear-receptor.com/content/1/1/8 Nucl Recept.]
+====Copyright====
+© 2003 Val et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. Val et al. Nuclear Receptor 2003 1:8   doi:10.1186/1478-1336-1-8 http://www.nuclear-receptor.com/content/1/1/8
+Original file name: Figure 2.  1478-1336-1-8-2-l.jpg http://www.nuclear-receptor.com/content/1/1/8/figure/F2 (cartoon cropped from full image)
-Val et al. Nuclear Receptor 2003 1:8   doi:10.1186/1478-1336-1-8 http://www.nuclear-receptor.com/content/1/1/8
+{{Footer}}
-© 2003 Val et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
 [[Category:Adrenal]] [[Category:Testis]] [[Category:Ovary]] [[Category:Molecular]]