Computed Tomography

Introduction

Micro-computed tomography apparatus

Computed Tomography or computed axial tomography (CAT or CT scan) began in 1970's using x-ray and a computer to produce images either as individual slices or reconstructed to give three dimensional (3D) views of specific anatomical regions or structures. This page currently has links to x-ray micro-CT movies of early mouse development. (More? Mouse Development).

Other potential developmental research imaging techniques include: positron emission tomography (PET), single photon emission computed tomography, magnetic resonance imaging, computed tomography, optical bioluminescence, fluorescence and high frequency ultrasound.

Links: original Tomography page

Some Recent Findings

Rapid Three-Dimensional Phenotyping of Cardiovascular Development in Mouse Embryos by Micro-CT with Iodine Staining. Degenhardt K, Wright AC, Horng D, Padmanabhan A, Epstein JA. Circ Cardiovasc Imaging. 2010 Feb 27. PMID: 20190279

Johnson JT, Hansen MS, Wu I, Healy LJ, Johnson CR, Jones GM, Capecchi MR, Keller C. Virtual histology of transgenic mouse embryos for high-throughput phenotyping. PLoS Genet. 2006 Apr;2(4):e61. PMID: 16683035 | PLoS

Early Mouse Development MicroCT

Mouse E9.5^[1]
Mouse E10.5^[1]
Mouse E11.5^[1]
Mouse E11.5^[1]
Mouse E12.5^[1]
Mouse E14.5^[2]

Movies

	Flash version Quicktime version
Mouse E11.5 microCT scan^[3]

Links: Flash - Computed Tomography | Quicktime - Computed Tomography

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 <pubmed>16683035</pubmed>| PLoS Genetics
↑ <pubmed>18713865</pubmed>| PNAS
↑ <pubmed>16683035</pubmed>

Search Pubmed

Search Pubmed: Embryo Computed Tomography | Computed Tomography | Micro-computed tomography apparatus

External Links

Duke Center for In Vivo Microscopy A 4D Atlas and Morphologic Database
- Normal C57BL/6 mouse embryos from embryonic day E10.5 to E19.5
- Normal C57BL/6 mouse neonates from post-natal day 0 to 32
- Mutant mouse embryos with cardiac septation defects (conditional ablation of the Smoothened receptor gene, Mef2C-AHF-Cre;Smo^{flox/-^mutants)}

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link

Cite this page: Hill, M.A. (2024, May 6) Embryology Computed Tomography. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Computed_Tomography

What Links Here?

[PMID16683035-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 <pubmed>16683035</pubmed>| PLoS Genetics

[2] <pubmed>18713865</pubmed>| PNAS

[3] <pubmed>16683035</pubmed>

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