Coelomic Cavity Development

From Embryology
Revision as of 16:28, 18 June 2014 by Z8600021 (talk | contribs)
Embryology - 12 Dec 2019    Facebook link Pinterest link Twitter link  Expand to Translate  
Google Translate - select your language from the list shown below (this will open a new external page)

العربية | català | 中文 | 中國傳統的 | français | Deutsche | עִברִית | हिंदी | bahasa Indonesia | italiano | 日本語 | 한국어 | မြန်မာ | Pilipino | Polskie | português | ਪੰਜਾਬੀ ਦੇ | Română | русский | Español | Swahili | Svensk | ไทย | Türkçe | اردو | ייִדיש | Tiếng Việt    These external translations are automated and may not be accurate. (More? About Translations)

Introduction

Mesoderm cartoon4.gif
coelom - (Greek, koilma = cavity) Term used to describe a fluid-filled cavity or space. Placental vertebrate development have both extraembryonic (outside the embryo) and intraembryonic (inside the embryo) coeloms.

The extraembryonic coeloms include the yolk sac, amniotic cavity and the chorionic cavity information on these spaces can also be found on placental development pages.

The intraembryonic coelom is initially a single space located in the lateral plate mesoderm, that will later form the 3 major body cavities: pleural, pericardial and peritoneal.


All intraembryonic cavities are fluid filled and developing organs push against a wall of the cavity, generating a double coat (serosal/adventital) surrounding an organ (for example the lungs). The serous membrane is the epithelium (squamous) and its associated underlying loose connective tissue.


Coelom Links: Introduction | Lecture - Week 3 Development | Lecture - Mesoderm Development | Placenta - Membranes | Category:Coelomic Cavity
Historic Embryology: 1891 peritoneal | 1897 human coelom | 1910 | 1924 serous

Some Recent Findings

  • Embryo-fetal erythroid megaloblasts in the human coelomic cavity[1] "The coelomic cavity is part of the extraembryonic mesoderm, surrounding amniotic cavity, embryo, and yolk sac in the early gestation. It is now believed to represent an important transfer interface and a reservoir of nutrients for the embryo. Coelocentesis by ultrasound-guided transvaginal puncture offers an easier access to the early human embryo, from 28 days post-fertilization. However, despite some studies about its biochemical composition being reported, our knowledge about the presence of cellular elements and their quality in this compartment are still limited. Here we studied human coelomic fluids sampled from 6.6 (48 days) to 10 weeks of gestation, demonstrating the presence of functional embryonic erythroid precursors, that is, megaloblasts in the coelomic cavity."
More recent papers
Mark Hill.jpg
PubMed logo.gif

This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.

  • This search now requires a manual link as the original PubMed extension has been disabled.
  • The displayed list of references do not reflect any editorial selection of material based on content or relevance.
  • References also appear on this list based upon the date of the actual page viewing.


References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability.

More? References | Discussion Page | Journal Searches | 2019 References

Search term: Coelomic Cavity Development

<pubmed limit=5>Coelomic Cavity Development</pubmed>

Objectives

  • Describe the development of the intra- and extra-embryonic coeloms.
  • Describe the processes involved in the development of the three divisions of the intra-embryonic coelom; pericardium, pleural cavities and peritoneum.
  • Describe the fate of the extra embryonic coelom.
  • Describe the development of the diaphragm.

Development Overview

Extraembryonic Coelom
cavity surrounding the developing embryo
coelomic portalstransient communication between extra/intracoelom
Intraembryonic Coelom
horseshoe shaped structure forms 3 main cavities
Neural Tube


pericardial cavity
Ventricular space
L/R pleural cavities
Spinal canal
peritoneal cavity
(More? Neural System Development)

Extraembryonic Coelom

Human embryo (week 4) extra embryonic coeloms.
Human embryo enclosed in extraembryonic membranes surrounding coeloms.

Amniotic cavity

The fluid-filled (amniotic fluid) extraembryonic coelom (cavity) formed initially by epiblast and then lined by ectoderm and surrounding extraembryonic mesoderm. In humans, it forms the innermost fetal membrane, produces amniotic fluid expanding to eventually fuse with the chorionic membrane during week 8 of development. This fluid-filled sac initially lies above the trilaminar embryo disc and with embryonic disc folding this sac is drawn ventrally to enclose (cover) the entire embryo, then fetus. The presence of this membrane led to the description of reptiles, bird, and mammals as "amniotes".

Chorionic cavity

The fluid-filled extraembryonic coelom (cavity) formed initially from trophoblast and extraembryonic mesoderm that forms placenta. Chorion and amnion are made by the somatopleure. The chorion becomes incorporated into placental development. The avian and reptilian chorion lies beside the egg shell and allows gas exchange. In humans, this cavity is lost during week 8 when the amniotic cavity expands and fuses with the chorion.

Yolk sac

An extraembryonic membrane which is endoderm origin and covered with extraembryonic mesoderm. Yolk sac lies outside the embryo connected initially by a yolk stalk to the midgut with which it is continuous with. The endodermal lining is continuous with the endoderm of the gastrointestinal tract. The extra-embryonic mesoderm differentiates to form both blood and blood vessels of the vitelline system. In reptiles and birds, the yolk sac has a function associated with nutrition. In mammals the yolk sac acts as a source of primordial germ cells and blood cells. Note that in early development (week 2) a structure called the "primitive yolk sac" forms from hypoblast, this is an entirely different structure.

Intraembryonic Coelom

peritoneal and retroperitoneal

Stage 13 image 073.jpg

Week 5 pericardial and peritoneal cavities

Pericardial Cavity

Links: Cardiovascular System Development

Pleural Cavity

Links: Respiratory System Development

Peritoneal Cavity

Links: Gastrointestinal Tract Development

Week 8

Pleural

Stage 22 image 200.jpg

Peritoneal

Stage 22 image 203.jpg

Carnegie stage 22

Mesentery and Retroperitoneal

Bailey301-303.jpg

Stages in the development of the bursa omentalis, the greater omentum, and the fusion of the latter with the transverse mesocolon.


Gray1040.jpg



Links: Gastrointestinal Tract Development

Mesothelium

The epithelial covering of coelomic organs and also line their cavities.

  • Contribute to the vasculature of the heart and the intestinal tract.
  • Undergo epithelial-mesenchymal transition (EMT), migration, and differentiation into endothelial cells, vascular smooth muscle cells, and pericytes.
    • contribute most of the vascular smooth muscle to the respiratory and gastrointestinal tract. (Remainder derived from endothelium?)

References

  1. <pubmed>20533375</pubmed>


Reviews

Articles

<pubmed>10457021</pubmed>

Search PubMed

Search Pubmed: Coelomic Cavity Development | pericardial cavity development | pleural cavity development | peritoneal cavity development

Additional Images

Historic


Terms

  • atresia- obstruction.
  • eppiglottis- develops from hypobrachial eminence.
  • fistula- abnormal comunication.
  • hypopharyngeal eminence- fusion of 3rd pharyngeal arches, precursor of root of tongue.
  • laryngotracheal groove- forms on anterior (ventral) wall of pharynx, gives rise to larynx, trachea, respiratory tree.
  • larynx- lining from endoderm, cartilage from pharyngeal arch 4 and 6.
  • lung buds- primordia of lungs.
  • parietal pleura-outer lining of pleural cavity derived from epithelia of pericardioperitoneal canals from intraembryonic coelom.
  • pleural cavity- walls derived from pericardioperitoneal canals -> intraembryonic coelom ->coelomic spaces -> lateral mesoderm -> mesoderm.
  • pleuropericardial fold- restricts the communication between pleural cavity and pericardiac cavity, contains cardinal vein and phrenic nerve.
  • pleuroperitoneal membrane- forms inferiorly at transverse septum to separate peritoneum from pleural cavity.
  • septum transversum- mesoderm separating thoracic cavity and yolk sac, forms central tendon of diaphragm (and some of liver?).
  • stenosis- narrowing
  • surfactant- a detergent secreted by Type 2 alveolar cells between alveolar epithelium. Functions to lower surface tension, allowing lungs to remain inflated.
  • visceral pleura- inner lining of pleural cavity derived from contact epithelia with lung bud of pericardioperitoneal canals from intraembryonic coelom.



System Links: Introduction | Cardiovascular | Coelomic Cavity | Endocrine | Gastrointestinal Tract | Genital | Head | Immune | Integumentary | Musculoskeletal | Neural | Neural Crest | Placenta | Renal | Respiratory | Sensory | Birth


Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link



Cite this page: Hill, M.A. (2019, December 12) Embryology Coelomic Cavity Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Coelomic_Cavity_Development

What Links Here?
© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G