Abnormal Development - Herbal Drugs

Introduction

The following herbal drugs have been used for a number of different maternal conditions: Ginkgo Biloba, Kava (Piper methysticum), St. John's wort (Hypericum perforatum), Tian Ma (Gastrodia elata), Valerian (Valeriana officinalis). In some cases very little is known about the potential teratogenic effects of these drugs (More? Herbal Drugs).

HSTAT St. John's Wort | Appendix II: Side Effects, Adverse Effects, Precautions, and Warnings "The safety of using hypericum during pregnancy or lactation has not been proven so it should be avoided." "St. John's wort induces the CYP 450 3A4 metabolic pathway which is also used by many prescription drugs used to prevent conditions (transplant rejection or pregnancy oral contraceptives), health care providers should alert patients about these potential drug interactions."

Links: Abnormal Development - Herbal Drugs

Some Recent Findings

References

Reviews

Saunders EJ, Saunders JA. Drug therapy in pregnancy: the lessons of diethylstilbestrol, thalidomide, and bendectin. Health Care Women Int. 1990;11(4):423-32.

Articles

McBride WG. Prescription drugs in the first trimester and congenital malformations. Aust N Z J Obstet Gynaecol. 1992 Nov;32(4):386.

Search Pubmed

June 2010 "infant drug clearance rates" All (168) Review (22) Free Full Text (45)

Search Pubmed: herbal drugs in pregnancy

UNSW Embryology Links

Abnormal Development
Abnormal Development- Australian Statistics | Abnormalities by Systems
Prenatal Diagnosis
Genetic Abnormalities | Down Syndrome | Edwards Syndrome | Fragile X | Lesch-Nyhan Syndrome
Maternal Factors | Maternal Diabetes | Maternal Hyperthermia | Neural Tube Defects | Fetal Alcohol Syndrome | Smoking | Chemical | Drugs | Illegal Drugs | Radiation | Heavy Metal | Iodine Deficiency | Viral Infection | Rubella | Polio | Parvovirus | Varicella | Bacterial Infection | Malaria | Toxoplasmosis | Autism
Fetal Origins Hypothesis
Intrauterine Growth Retardation
Twinning

External Links

United Nations International Drug Control Programme
Australian Drug Foundation (ADF)
Centre for Education and Information on Drugs and Alcohol (CEIDA) (Australia)
Child Health and Safety (Australia)
NIDA (USA)- Consequences of Prenatal Drug Exposure
Australian Medicines Handbook (no electronic version yet)
Australian Congenital Anomalies Monitoring System (ACAMS)
Australian Institute of Health and Welfare (AIHW)

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Cite this page: Hill, M.A. (2024, May 19) Embryology Abnormal Development - Herbal Drugs. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Herbal_Drugs

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