Developmental Mechanism - Epithelial Invagination

Notice - Mark Hill

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Introduction

Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.

Mechanism - "a process, technique, or system for achieving a result".

Some Recent Findings

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Cite this page: Hill, M.A. (2026, August 20) Embryology Developmental Mechanism - Epithelial Invagination. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Mechanism_-_Epithelial_Invagination

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