Mifepristone

From Embryology

Introduction

Mifepristone molecular structure

(RU 486) A progesterone receptor antagonist similar in structure to the natural hormone progesterone, which is used medically as a birth control drug. Progesterone is a steroidal hormone of the progestogens class, which has many roles in the female. Functions include regulation of the menstrual cycle, uterine changes, maintaining pregnancy and effects on systems throughout the body. Biological sources include: adrenal glands, gonads (corpus luteum), brain, and placenta. Male progesterone has a suggested role in neural development. Progesterone is also used clinically as a part of hormone replacement therapy (HRT) in women. The human progesterone receptor has two isoforms (PRA and PRB). Commercial drug names include Mifegyne and Mifeprex.

References

Reviews

<pubmed>20933118</pubmed> <pubmed>20102310</pubmed> <pubmed>20004266</pubmed>

Articles

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Cite this page: Hill, M.A. (2024, June 26) Embryology Mifepristone. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Mifepristone

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G