Late Cardiovascular Development

Introduction

In lecture 7 -Early Vascular Development there was an introduction to the origins of the cardiovascular system. This second lecture will now focus on the extensive changes and remodeling that now occur in this system during later development. In addition there will be

Lecture Objectives

Describe the development of primary and secondary atrial septa and the ventricular septum.
Explain the changes occurring in the bulbis cordis and truncus arteriosus in its transformation from a single to a double tube.
Describe the development of the aortic arches on the right and left sides from the fetus to the adult.
Describe the development of arteries and veins.
Describe the major cardiovascular developmental abnormalities.

Textbook references

Human Embryology (3rd ed.) Larson Chapter 7 p151-188 Heart, Chapter 8 p189-228 Vasculature
The Developing Human: Clinically Oriented Embryology (6th ed.) Chapter 14: p304-349

Other textbooks

Before we Are Born (5th ed.) Moore and Persaud Chapter 12; p241-254
Essentials of Human Embryology Larson Chapter 7 p97-122 Heart, Chapter 8 p123-146 Vasculature
Human Embryology Fitzgerald and Fitzgerald Chapter 13-17: p77-111

Recent reviews

Yutzey KE, Kirby ML. Wherefore heart thou? Embryonic origins of cardiogenic mesoderm. Dev Dyn. 2002 Mar;223(3):307-20. Review. PMID: 11891982
Three-dimensional reconstruction of gene expression patterns during cardiac development. Soufan AT, Ruijter JM, van den Hoff MJ, de Boer PA, Hagoort J, Moorman AF. Physiol Genomics. 2003 May 13;13(3):187-95. Review. PMID: 12746463
Moorman A, Webb S, Brown NA, Lamers W, Anderson RH. Development of the heart: (1) formation of the cardiac chambers and arterial trunks. Heart. 2003 Jul;89(7):806-14. PMID: 12807866
Bruneau BG. Transcriptional regulation of vertebrate cardiac morphogenesis. Circ Res. 2002 Mar 22;90(5):509-19. Review. PMID: 11909814

Abnormalities

responsible for the following malformations: patent ductus arteriosus (P.D.A.); atrial septal defects (A.S.D.) and ventricular septal defects (V.S.D.); tetralogy of Fallot.

Glossary Links

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Course Content 2009

Cite this page: Hill, M.A. (2024, June 26) Embryology 2009 Lecture 21. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/2009_Lecture_21

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