Morula: Difference between revisions
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== Some Recent Findings == | == Some Recent Findings == | ||
[[File: | [[File:Human_embryo_day_3.jpg|thumb|300px|Human morula (day 3)<ref name="PMID19924284" />]] | ||
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* '''Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage'''<ref name="PMID20890283"><pubmed>20890283</pubmed>| [http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.1686.html Nat Biotechnol.]</ref> "We report studies of preimplantation human embryo development that correlate time-lapse image analysis and gene expression profiling. By examining a large set of zygotes from in vitro fertilization (IVF), we find that success in progression to the blastocyst stage can be predicted with >93% sensitivity and specificity by measuring three dynamic, noninvasive imaging parameters by day 2 after fertilization, before embryonic genome activation (EGA)." | * '''Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage'''<ref name="PMID20890283"><pubmed>20890283</pubmed>| [http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.1686.html Nat Biotechnol.]</ref> "We report studies of preimplantation human embryo development that correlate time-lapse image analysis and gene expression profiling. By examining a large set of zygotes from in vitro fertilization (IVF), we find that success in progression to the blastocyst stage can be predicted with >93% sensitivity and specificity by measuring three dynamic, noninvasive imaging parameters by day 2 after fertilization, before embryonic genome activation (EGA)." | ||
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==Mouse Morula== | |||
[[File:Mouse-morula_01.jpg|300px]] | |||
Mouse 4 cell morula stage development<ref><pubmed>20405021</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854157 PMC2854157] | [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0010160 PLoS]</ref> | |||
==References== | ==References== |
Revision as of 12:28, 12 October 2010
Introduction
(Latin, morula = mulberry) An early stage in post-fertilization development when cells have rapidly divided to produce a solid mass of cells (12-15 cells) with a "mulberry" appearance. This stage is followed by formation of a cavity in this cellular mass blastocyst stage. In humans, morula stage of development occurs during the first days of the first week following fertilization. This developmental stage is followed by formation of a cavity, the blastocoel, which defines formation of the blastocyst.
- Links: Fertilization | Week 1 | Morula | Blastocyst
Some Recent Findings
|
Mouse Morula
Mouse 4 cell morula stage development[3]
References
- ↑ 1.0 1.1 <pubmed>19924284</pubmed>| PMC2773928 | PLoS One
- ↑ <pubmed>20890283</pubmed>| Nat Biotechnol.
- ↑ <pubmed>20405021</pubmed>| PMC2854157 | PLoS
Articles
<pubmed>19289087</pubmed> <pubmed>20157423</pubmed>
Search PubMed
Search Pubmed: morula development | blastomere development |
Glossary Links
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Cite this page: Hill, M.A. (2024, June 24) Embryology Morula. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Morula
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G